Rotator cuff syndrome

This study compares three different schedules of shock wave therapy for people with partial rotator cuff tears, a common cause of shoulder pain and limited movement. The goal is to see if a high-frequency, short-course treatment (daily sessions for one week) works as well as or b…

This trial tests whether an injection of platelet-rich plasma (PRP) made from a patient's own blood can help heal partial tears of the supraspinatus tendon in the shoulder. One hundred adults with confirmed tears will receive either PRP plus standard physical therapy or therapy a…

This trial tests whether using a piece of the patient's own biceps tendon as a graft can improve rotator cuff repair and reduce the risk of re-tear. About 90 working-age adults with supraspinatus tears will be randomly assigned to either standard arthroscopic repair or repair wit…

This study tests whether injecting a patient's own fat-derived stem cells into the shoulder muscle, alongside standard surgery, improves healing for torn rotator cuffs. Thirty adults with a confirmed tear will be randomly assigned to surgery alone or surgery plus stem cell inject…

This study tests whether injecting stem cells from umbilical cords can help heal partial rotator cuff tears in the shoulder. Thirty-eight adults with ongoing shoulder pain will receive either a high or medium dose of stem cells or a placebo. The main goal is to see if the tear sh…

This study looks at whether adding stem cells from the shoulder bursa and platelet-rich plasma (PRP) to standard rotator cuff repair helps the tendon heal better. About 200 adults with full-thickness supraspinatus tears will be followed for a year. Researchers will compare those …

This study tests whether using a piece of the patient's own biceps tendon as a patch during rotator cuff repair helps the torn tendon heal better. 80 adults with medium to large tears will be randomly assigned to standard repair or repair with the patch. Researchers will measure …

This study looks at three ways to treat a specific type of shoulder fracture (greater tuberosity fracture) that also involves a rotator cuff injury. The three options are: non-surgical care, surgery right away, or surgery after a delay. The goal is to see which approach leads to …

This study looks at whether estradiol patches can improve shoulder healing after rotator cuff repair in post-menopausal women. About 58 women will receive either an estradiol patch or a placebo patch for three months after surgery. The goal is to see if the hormone helps reduce p…

This study compares a telerehabilitation system called Band Connect to standard in-person physical therapy for people recovering from rotator cuff repair surgery. The Band Connect uses smart handles and resistance bands that connect to a phone app to guide exercises and track pro…

This early-phase trial tests whether tendon stem cells can help rotator cuff tears heal better after surgery. About 107 adults with small to medium tears will receive either standard repair or repair plus stem cells placed at the injury site. The study will check for side effects…

This study will check if a new physical exam called Said's test can accurately diagnose biceps tendon injuries in the shoulder. Researchers will test 144 adults, including those with shoulder injuries and healthy volunteers. Two doctors will perform the new test and standard test…

This study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. T…

This study compares task-oriented occupational therapy to standard rehab for people recovering from rotator cuff surgery. Thirty participants will be randomly assigned to one of two groups, attending 40-minute sessions twice a week for 10 weeks. The goal is to see if focusing on …

This study looks at whether adding a specific hands-on technique called Mobilization With Movement (MWM) to standard exercises can better reduce pain and improve shoulder function in people with rotator cuff tendinopathy. About 60 adults with chronic shoulder pain will be split i…

This study compares two manual therapy techniques—myofascial trigger point release and the Neil Asher Technique—for treating rotator cuff syndrome, a common cause of shoulder pain and limited movement. Thirty-six adults aged 40 to 60 with mild to moderate rotator cuff syndrome wi…

This study looks at whether 4 weeks of low-intensity shoulder exercises, done with or without a blood flow restriction cuff, can reduce pain and improve function in people with rotator cuff-related shoulder pain. 34 adults with long-lasting shoulder pain will be randomly assigned…

This study tests a new type of nerve block (PENG block) for people with chronic shoulder pain that hasn't improved with other treatments. 45 adults will get an ultrasound-guided injection of numbing medicine and steroid. Researchers will measure pain, shoulder function, and satis…

This study compares two types of full can exercises—concentric and eccentric—for people with partial rotator cuff tears. Sixty participants will do one type of exercise plus standard physiotherapy for 6 weeks. Researchers will measure changes in shoulder muscle structure, pain, a…

This study tests whether adding high-intensity laser therapy to standard physical therapy helps people recover better after arthroscopic rotator cuff repair. 46 adults aged 30-70 with shoulder pain will be randomly assigned to receive either real laser therapy or a sham treatment…

This study tests whether a mobile app with AI-guided exercise videos and reminders helps people recover better after arthroscopic rotator cuff repair compared to standard paper instructions. About 102 adults who need surgery will be randomly assigned to use the app or follow pape…

This study tests whether adding a gentle back-mobilization technique to standard shoulder therapy can improve pain, movement, and function in people with rotator cuff injuries. Forty adults with chronic shoulder pain will receive either shoulder mobilization alone or combined wit…

This study compares two exercise programs for people with rotator cuff-related shoulder pain. One group gets a standard, fixed program, while the other gets the same exercises but with personalized touches like preferred music, choice of exercises, and motivational feedback. Rese…

This study tests whether a special device called H-Wave can help people recover faster and with less pain after rotator cuff repair surgery. About 80 adults aged 18-64 will either receive standard care or standard care plus the H-Wave device. Researchers will track pain, medicati…

This study tests whether a mental exercise program called graded motor imagery can reduce pain and improve shoulder function after surgery for a massive rotator cuff tear. The program includes tasks like recognizing shoulder positions, imagining movements, and using a mirror to t…

This early-phase trial will test four orthobiologic treatments—PRP, bone marrow concentrate, hyaluronic acid, and nanofat—in 300 adults with various muscle, joint, tendon, or bone conditions. The goal is to see if these natural substances can reduce pain and improve joint functio…

This study tests whether a home-based virtual reality (VR) exercise program is practical and helpful for people with shoulder pain lasting more than three months. Thirty adults aged 16 and older with rotator cuff syndrome, frozen shoulder, or shoulder instability will use a VR he…

This study compares two surgical techniques for the biceps tendon—tenotomy (cutting the tendon) and tenodesis (reattaching it)—in 50 adults aged 50-70 undergoing rotator cuff repair. The goal is to see which method leads to less pain, better shoulder function, and stronger grip a…

This study looks at whether using a pillow placed behind the shoulder after rotator cuff repair surgery can lower pain and improve sleep. About 126 adults aged 40 to 70 will choose whether to use the pillow or not. Their pain, sleep quality, and shoulder function will be checked …

This study looks at whether teaching people with rotator cuff syndrome the best sleeping positions can improve their sleep quality while they undergo physical therapy. Researchers will compare two groups: one getting standard physical therapy, and another getting physical therapy…

This study looks at whether a mobile app can help people with common pains (neck, shoulder, back, or knee) do their prescribed home exercises more regularly. About 30 adults will be split into two groups: one using the app and one doing traditional exercises. The goal is to see i…

This study looks at whether starting gentle shoulder exercises soon after rotator cuff repair leads to better recovery than waiting six weeks. About 86 adults who have surgery for a torn rotator cuff will be randomly assigned to either early or delayed rehabilitation. Researchers…

This study looks at whether doing extra tissue release during arthroscopic rotator cuff repair can prevent shoulder stiffness after surgery. About 50 adults with small-to-medium rotator cuff tears will be randomly assigned to get either the standard repair or the repair plus extr…

This study tests four different virtual reality (VR) exercises in 30 adults who have had rotator cuff-related shoulder pain for at least 6 months. Participants will do weekly VR sessions for four weeks and complete questionnaires about their arm function, pain, and fear of moveme…

This study tests a special brace with a built-in pillow to see if it helps people sleep better after rotator cuff surgery. About 100 patients will either use the pillow brace or a standard brace. The goal is to reduce nighttime pain and improve sleep quality, which may help recov…

This study will follow 50 adults having arthroscopic rotator cuff repair to see if a condition called central sensitization—where the nervous system is overly sensitive to pain—affects their recovery. Before surgery and 3 months after, researchers will measure pain and shoulder f…

This study will use portable ultrasound to measure the thickness of forearm muscles and tendons in 90 adults with rotator cuff-related shoulder pain. Researchers want to see if these measurements change based on how long someone has had shoulder pain. They will also measure hand …

This study looks at whether 'central sensitization' — a condition where the nervous system is overly sensitive to pain — affects how well physical therapy works for people with partial rotator cuff tears. Researchers will follow 60 adults aged 18-65 who have had shoulder pain for…

This study aims to translate and adapt a widely used questionnaire for musculoskeletal problems into Urdu. Researchers will enroll 110 Urdu-speaking adults, including patients with muscle or joint issues and healthy volunteers. The goal is to create a validated tool to measure sy…

This study looks at how patients feel when reading their own medical notes. Some will read the original doctor's note, others will read a simpler version written by artificial intelligence. Researchers want to see if the AI summary changes how much patients trust their doctor or …

This study looks at how stress on the shoulder bone (acromion) changes after reverse shoulder replacement surgery. Researchers will use CT and MRI scans from 13 patients to create computer models that show where bone stress is highest. The goal is to better understand and prevent…

This study looks at two different ways to perform reverse total shoulder replacement in 130 people aged 60-85 with severe shoulder arthritis and torn rotator cuffs. The goal is to see which technique leads to better muscle activity and arm movement. Participants will have their s…

This study looks at whether metabolic syndrome (a cluster of conditions like high blood pressure and excess belly fat) makes it harder to recover from a rotator cuff injury. Forty adults with rotator cuff tears will be split into two groups—those with and without metabolic syndro…

This study tests a decision support system called SmaRTWork to help people on sick leave due to muscle or back pain return to work. About 298 adults in Norway will either use the system or receive usual care. The main goal is to see if the tool helps them return to work sustainab…

This study looks at how having a structured, values-based conversation affects people's decisions about diagnostic imaging tests for common musculoskeletal conditions like arthritis, carpal tunnel syndrome, and tendon problems. About 220 adults from a specialty clinic will read a…