Rotator cuff syndrome

This early study tests a new device called SINEFIX to repair small rotator cuff tears (up to 2 cm) in 9 adults. The implant is placed during keyhole surgery to reattach the torn tendon to the bone. Researchers will use MRI scans to check if the tendon heals properly and if there …

This study is testing a special implant (Tapestry) that helps repair a key shoulder tendon (subscapularis) during shoulder replacement surgery. About 100 adults with shoulder arthritis or injury will be followed for 2 years to see if the tendon heals better with the implant. The …

This study follows 200 adults getting a shoulder replacement with the Zimmer Trabecular Metal Reverse Shoulder System. It aims to see how long the implant lasts and how well it relieves pain and improves movement in people with conditions like arthritis, fractures, or failed prio…

This phase 2 trial tests whether a patient's own fat-derived cells (stromal vascular fraction) can improve healing after surgical repair of a chronic rotator cuff tear. The study enrolls 56 adults aged 45-65 with full-thickness tears who have not improved with physical therapy. T…

This study tests whether adding stem cells from a patient's own fat tissue to standard rotator cuff surgery can improve healing and reduce recovery time. About 30 adults with shoulder tendon tears will receive the stem cell injection during surgery. The goal is to see if this sim…

This study is following 110 people who received a Tornier HRS shoulder replacement to see how well it improves pain and function. Participants have conditions like arthritis, fractures, or rotator cuff tears. The goal is to collect long-term safety and performance data for regula…

This study tests whether injecting atelocollagen and hyaluronic acid during rotator cuff surgery improves healing. 124 people aged 40-75 with confirmed tears are enrolled. They receive one or both injections during arthroscopic repair and are followed for 2 years with MRI scans a…

This study compares two common injections—platelet-rich plasma (PRP) and corticosteroids—given during arthroscopic rotator cuff repair. 387 adults with full-thickness supraspinatus tears are randomly assigned to receive PRP, corticosteroid, or a placebo injection during surgery. …

This study looks at the best way to treat partial rotator cuff tears in people who also have stiff shoulders. Half of the 80 participants will have early surgery, while the other half will follow a structured rehab program with the option of surgery later if needed. The goal is t…

This study follows 200 adults who receive the Shoulder iD™ implant to treat severe rotator cuff tears or shoulder arthritis. Researchers measure how well the shoulder works and how often the implant needs to be fixed or replaced over 10 years. Participants attend regular check-up…

This study compares two ways to recover after reverse total shoulder replacement: using a smartphone app (mymobility) for home exercises versus standard in-person physical therapy. Researchers will enroll 100 adults to see if the app works just as well. The main goal is to measur…

This early-phase trial tests whether injecting special donor cells (E-CEL UVEC) into the shoulder during rotator cuff surgery is safe and might improve healing. Twenty adults aged 45-70 with full-thickness tears will receive the cells at the repair site. The main goal is to check…

This study is testing a shoulder replacement device called the Medacta Shoulder System in 100 people with shoulder arthritis or rotator cuff tears. The goal is to see how well the implant works after 2 years, focusing on shoulder function, safety, and patient satisfaction. Partic…

This study tests a special implant called TAPESTRY that is placed during shoulder surgery to support healing of torn rotator cuff tendons. About 170 adults with partial or full-thickness tears will receive the implant and be followed for 6 months. The main goal is to see if the i…

This study is tracking 175 people who receive a Biomet Comprehensive Reverse Shoulder implant to see how much their pain and shoulder function improve over one year and beyond. Participants have severe shoulder problems like arthritis or a torn rotator cuff that cannot be repaire…

This study follows 99 people who received a specific shoulder replacement system to see how well it works and if it is safe. Participants had severe shoulder arthritis, a torn rotator cuff, or a failed prior shoulder replacement. The main goal is to track how long the implant las…

This study follows 200 adults who received the Medacta Shoulder System to treat shoulder problems like arthritis, fractures, or to replace a previous implant. Researchers are checking how long the implant lasts, how well the shoulder works, and any side effects. The goal is to co…

This study tests a new flexible suturing system with anchors (FSSA) to repair full-thickness rotator cuff tears. About 100 people who have had this surgery will get an MRI one year later to check if the tendon has healed. The goal is to see if this device helps tendons heal more …

This study tests a new injection called NEMO-103 to see if it makes shoulder MRI pictures clearer for diagnosing problems like torn tendons or cartilage. About 85 adults with known or suspected shoulder issues will get both a regular MRI and one with the injection. The goal is to…

This study compares three non-surgical treatments—exercise therapy, shockwave therapy, and ultrasound-guided irrigation—against a wait-and-see approach for people with painful calcium deposits in the shoulder. About 116 participants with confirmed calcific tendinopathy will be ra…

This study compares physical therapy delivered through video calls to traditional in-person therapy for 50 young elite baseball players with rotator cuff problems. The goal is to see if remote therapy is as effective at improving shoulder function and reducing pain, and whether i…

This study tests a modified surgical technique for people with massive, irreparable rotator cuff tears. The procedure moves the lower trapezius tendon to help restore shoulder function. Twenty-five patients will be followed to see if pain decreases and shoulder ability improves.

This study tests whether giving people with rotator cuff shoulder pain regular updates on their progress (like pain scores and strength) helps them recover better. 56 adults aged 18–35 will either get standard rehab or standard rehab plus these progress updates. The goal is to se…

This study looks at whether adding kinesio taping to standard rehab after rotator cuff surgery helps reduce pain and improve shoulder function. Fifty adults aged 18 to 70 who had surgery for a torn rotator cuff are randomly assigned to get either standard rehab alone or standard …

This study tests whether a specific type of exercise called eccentric contraction (lengthening muscles under tension) can help people with shoulder pain syndrome. Sixty adults aged 18-70 with rotator cuff tendinitis will do either eccentric exercises plus standard therapy or stan…

This study looks at whether kinesio taping can quickly reduce pain, improve how far you can move your shoulder, and lessen fear of movement in people with rotator cuff syndrome. About 52 adults aged 18 to 65 with shoulder pain for at least 3 months will take part. Researchers wil…

This small study tests a procedure called radiofrequency ablation for people with chronic shoulder pain that hasn't improved with standard treatments like physical therapy or injections. The treatment uses heat to calm the nerves that send pain signals from the shoulder joint. Te…

This study looks at two different hands-on therapy methods (Mulligan and PNF) added to standard physical therapy for people with partial rotator cuff tears. 45 adults aged 30-70 will be split into three groups to see which approach best reduces pain, improves shoulder movement, a…

This study tests whether adding perturbation-based exercises (unexpected movements that challenge balance) to standard physiotherapy can improve pain, strength, and shoulder function in people with partial rotator cuff tears. Sixty adults aged 18–65 will be randomly assigned to e…

This study compares two ways to help people with shoulder pain activate important muscles: using real-time ultrasound images versus standard verbal or visual feedback. About 26 adults with shoulder pain will do exercises in a lab, and researchers will measure muscle activity and …

This study compares two recovery programs after rotator cuff repair surgery. One group follows standard care—wearing a sling for 6 weeks with limited movement. The other group starts moving sooner, guided by comfort rather than strict restrictions. Researchers will measure should…

This study tests a device called RELAY that delivers both local anesthetic and mild electrical pulses to nerves after shoulder or foot surgery. The goal is to provide up to 28 days of pain relief, much longer than current options. About 50 adults undergoing specific surgeries wil…

This study looks at whether wearing a sling for three weeks after reverse shoulder replacement is better than wearing it for only three days. About 100 people having shoulder surgery at Duke University will be randomly assigned to one of the two groups. Researchers will track com…

This pilot study aimed to compare a single injection of connective tissue matrix (CTM) against a standard corticosteroid shot for treating rotator cuff tendinopathy. Participants would have been randomly assigned to one of the two injections and followed for six months with quest…

This study tests if a biceps tendon cutting procedure (tenotomy) done in the doctor's office with a tiny camera and local anesthesia works as well as the same surgery in an operating room. 14 adults with shoulder pain from biceps or rotator cuff problems will be enrolled. The mai…

This study explores whether adding motor imagery (mentally practicing shoulder movements) to standard physical therapy improves muscle activity, pain, and function after arthroscopic rotator cuff repair. About 36 adults who have had this surgery will be split into two groups: one…

This study looks at whether strengthening the latissimus dorsi muscle can improve shoulder space, reduce pain, and boost function in people with rotator cuff tendinopathy. 47 adults aged 18-50 with ongoing shoulder pain will be split into three groups: rotator cuff exercises only…

This study compares two types of injections for people with shoulder pain caused by rotator cuff tendinopathy. One injection, CTM Boost, is made from donated placental tissue, and the other, PRP, uses a patient's own blood. The goal is to see if CTM Boost works as well as PRP at …

This study looks at how the position and angle of surgical anchors used in rotator cuff repair affect cyst formation and tendon healing. Researchers will use MRI scans to measure cyst volume and assess tendon recovery in 70 adults aged 18–70 undergoing primary arthroscopic repair…

This study looked at whether having more frequent contact with a clinician (at least once a week) improves satisfaction for people with long-lasting musculoskeletal conditions. Participants were split into two groups: one with standard contact and one with extra check-ins via tex…

This study looks at how rotator cuff injuries—common causes of shoulder pain—might affect posture, trunk rotation, and balance. Researchers will compare 40 people with rotator cuff problems to 40 healthy volunteers, measuring things like spine curvature and balance using smartpho…

This study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…

This study looks at how the repaired rotator cuff tendon moves after surgery, which may affect recovery. 125 people getting rotator cuff repair will have small markers placed on the tendon during surgery. CT scans and MRIs over 5 years will track tendon position and healing, and …

This study looks at whether rotator cuff disease runs in families. Researchers will collect DNA, medical history, and family history from 400 people to understand genetic risk factors. The goal is to build a resource for future studies, not to test a new treatment.

This study explores whether the characteristics of bone marrow in the upper arm bone can predict how well a torn rotator cuff heals after surgery. Researchers will enroll 50 adults aged 18-75 with full-thickness tears and use MRI and CT scans to measure tendon healing. The goal i…

This study looks at ways to get patients to complete follow-up surveys after shoulder surgery. About 400 adults having shoulder arthroscopy will either receive education about the importance of surveys or get Amazon gift cards for completing them. The goal is to see which method …

This study was designed to follow patients with full-thickness rotator cuff tears over 10 years to see how their shoulder function and quality of life changed. It aimed to identify factors linked to improvement. However, the study was withdrawn before enrolling any participants, …

This study looks back at the medical records of about 4 million people who had physical or occupational therapy for muscle and joint problems. Researchers want to see if different ways of giving therapy lead to different results. No new treatments are tested—the goal is to learn …

This study aimed to see if a mobile monitoring tool could accurately identify surgical site infections (SSIs) in orthopedic surgery patients, compared to the usual manual review. The study was withdrawn before enrolling any participants, so no results are available. It was design…

This study gathers information from 160 people who received a shoulder implant to see how long the implant lasts and how safe it is. Participants have conditions like arthritis or fractures. The goal is to use this data to make better implants and help doctors and patients make i…

This study looks at how well a bio-inductive implant helps heal torn rotator cuff tendons in the shoulder. Researchers will use MRI scans at 3 and 6 months after surgery to check if the repair is holding and if there are any problems. About 20 people with partial or full tears wi…

This study follows 200 adults who received the Medacta Shoulder System to treat various shoulder issues like arthritis, fractures, or rotator cuff problems. The main goal is to see how long the implant lasts and how well the shoulder works after surgery. It is a post-market check…