New biologic injection takes on steroids for rotator cuff pain — but study pulled

NCT ID NCT06712290

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study aimed to compare a single injection of connective tissue matrix (CTM) against a standard corticosteroid shot for treating rotator cuff tendinopathy. Participants would have been randomly assigned to one of the two injections and followed for six months with questionnaires and physical tests. However, the study was withdrawn before enrolling any patients, so no data were collected.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Connective tissue matrix (CTM) injection

What this could lead to

If it works, this could offer a biologic alternative to steroid injections for shoulder pain, potentially with fewer side effects.

What could go wrong

This trial was withdrawn before enrolling any participants, so no results exist. The approach is very early and unproven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

disease of the tendon rotator cuff syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Allegheny Health Network Federal North Medical Office Building

    Pittsburgh, Pennsylvania, 15212, United States