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Sugar water injection may ease shoulder pain without surgery

NCT ID NCT07688902

Symptom relief Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study tests whether injecting a simple sugar water solution (5% dextrose) into or around a partial rotator cuff tear can reduce shoulder pain and improve function. Adults with chronic shoulder pain and a confirmed partial tear receive three ultrasound-guided injections over 9 weeks, plus a home exercise program. Researchers compare outcomes between those who get the injection directly into the tear versus around it.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
5% dextrose (sugar water) injection
What this could lead to
If it works, this could offer a simple, low-cost injection to ease shoulder pain and improve function without surgery.
What could go wrong
This is a small, early-stage trial with only 30 people. The effect may be small or no better than placebo, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2025

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of partial rotator cuff tear by a specialist physician after appropriate clinical examination and imaging evaluation * Shoulder pain and functional limitation lasting for at least 3 months * Clinically confirmed shoulder impingement findings, defined as at least one positive test among Neer, Hawkins-Kennedy, or painful arc tests * Age between 18 and 75 years * Ability to comply with the study procedures and attend follow-up visits regularly * Willingness to participate in the study and provide written informed consent Exclusion Criteria: * Advanced cognitive impairment or dementia preventing reliable completion of questionnaires * Refusal to participate in the study or inability to provide informed consent * Full-thickness rotator cuff tear * Major tendon pathology other than the supraspinatus tendon, such as full-thickness subscapularis tear or biceps tendon rupture * Advanced acromioclavicular joint osteoarthritis, marked impingement, or marked adhesive capsulitis * Advanced glenohumeral joint arthritis * Active infection, cellulitis, or dermatologic lesion at the injection site * Bleeding diathesis or anticoagulant use * Known allergy or intolerance to dextrose injection * Intra-articular shoulder injection, including steroid, platelet-rich plasma, or prolotherapy, within the last 3 months * Previous shoulder surgery * Uncontrolled diabetes mellitus, defined as HbA1c \>8.5%, or severe endocrine or metabolic disorder * Immunosuppression or active infection * Rheumatologic shoulder involvement * Neurological disease affecting shoulder movements * Pregnancy * Active malignancy

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Conditions

The condition(s) this trial relates to.

disease of the tendon rotator cuff syndrome Shoulder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Partial rotator cuff tears Rotator cuff tendinopathy Shoulder pain chronic Supraspinatus tendon tear

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ankara Bilkent City Hospital, Physical Medicine and Rehabilitation Hospital

    RECRUITING

    Ankara, Turkey (Türkiye)

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