Allegheny Singer Research Institute (also Known As Allegheny Health Network Research Institute)

This early study tests whether deep brain stimulation (DBS) can help people with severe opioid addiction who keep relapsing despite standard treatments. Only 3 participants will receive DBS to a brain region linked to reward and craving. The goal is to see if it is safe and can r…

This early-phase study tests a new treatment called Fast TIL for people with cancer that has spread to the lining around the lungs (pleura) or mesothelioma. The treatment uses immune cells taken from the patient's own pleural fluid, grown in a lab, and then given back through a c…

This study tests whether tamsulosin, a drug typically used for men with prostate problems, can help women recover bladder function faster after pelvic surgery. About 154 women who have trouble urinating after surgery will receive either the drug or a placebo. The goal is to see i…

This study tests three common pain management methods used during minimally invasive cancer surgery. About 48 adults having surgery for cancers like liver, stomach, or colorectal cancer will be randomly assigned to one of three groups: a nerve block with numbing medicine, the ner…

This study looks at whether resistance training and a high-protein drink after workouts can help women with breast cancer maintain muscle and reduce fat while undergoing chemotherapy. About 30 women will be randomly assigned to exercise and protein or standard care. The goal is t…

This study looks at two different exercise programs to see which one helps women gain muscle mass after finishing breast cancer treatment. Researchers will track changes in muscle and fat, as well as how well participants stick with the program. The goal is to find the best way t…

This study looks at how different supervised group exercise programs affect fitness and body composition in women who have completed breast cancer treatment. About 15 women aged 20-89 will try one of four resistance training regimens to see which best improves heart-lung fitness …

This study looks at whether placing a small lift under the lower back (sacral lift) can make the femoral vein bigger and easier to see on ultrasound. Researchers will compare vein size and artery overlap with and without the lift in 35 emergency department adults. The goal is to …

This study looks at how well the bones in the neck fuse together after surgery for degenerative disc disease. It compares a new titanium implant (Tritanium C) with a traditional bone graft. About 60 adults will be observed to see which material leads to faster and more successful…