Brain pacemaker tested for opioid addiction that Won't quit
NCT ID NCT04354077
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether deep brain stimulation (DBS) of the nucleus accumbens can help people with opioid use disorder who keep relapsing despite standard treatments. Only 3 participants will receive the implanted device. The main goal is to see if it is safe and whether it can help them stop using opioids.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
deep brain stimulation device
What this could lead to
If it works, this could point toward a new treatment option for people with severe opioid addiction that hasn't responded to other therapies.
What could go wrong
This is a very early, tiny pilot study with only 3 people. It is designed mainly to check safety, not effectiveness. Brain surgery carries serious risks like infection or bleeding.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AHN Allegheny General Hospital
RECRUITINGPittsburgh, Pennsylvania, 15212, United States
Contact
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Contact Email: •••••@•••••
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