Could donor cells boost rotator cuff repair? early trial begins
NCT ID NCT04057833
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests whether injecting special donor cells (E-CEL UVEC) into the shoulder during rotator cuff surgery is safe and might improve healing. Twenty adults aged 45-70 with full-thickness tears will receive the cells at the repair site. The main goal is to check for side effects in the first 11 days and up to a year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
E-CEL UVEC cells (donor cells injected at the repair site)
What this could lead to
If it works, this could lead to a way to help rotator cuff tears heal better after surgery, reducing re-tears and improving recovery.
What could go wrong
This is a very early phase 1 safety trial with only 20 people. It is not designed to prove effectiveness, and the cells may not improve healing or could cause side effects like pain or swelling.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital for Special Surgery
New York, New York, 10021, United States