Could donor cells boost rotator cuff repair? early trial begins
NCT ID NCT04057833
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests whether injecting special donor cells (E-CEL UVEC) into the shoulder during rotator cuff surgery is safe and might improve healing. Twenty adults aged 45-70 with full-thickness tears will receive the cells at the repair site. The main goal is to check for side effects in the first 11 days and up to a year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- E-CEL UVEC cells (donor cells injected at the repair site)
- What this could lead to
- If it works, this could lead to a way to help rotator cuff tears heal better after surgery, reducing re-tears and improving recovery.
- What could go wrong
- This is a very early phase 1 safety trial with only 20 people. It is not designed to prove effectiveness, and the cells may not improve healing or could cause side effects like pain or swelling.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital for Special Surgery
New York, New York, 10021, United States
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