Can your own fat cells fix a torn rotator cuff?

NCT ID NCT03332238

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether a patient's own fat-derived cells (stromal vascular fraction) can improve healing after surgical repair of a chronic rotator cuff tear. The study enrolls 56 adults aged 45-65 with full-thickness tears who have not improved with physical therapy. The cells are isolated from a small amount of belly fat during surgery and injected into the repair site. Researchers will measure shoulder strength, pain, and function over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
stromal vascular fraction cells from the patient's own fat tissue
What this could lead to
If it works, this could lead to a treatment that improves muscle and tendon healing after rotator cuff surgery, reducing pain and weakness.
What could go wrong
This is a small, early-phase trial (56 people) with no control group for comparison. The cells may not improve outcomes, and the procedure involves liposuction and surgery risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MUSCLE ATROPHY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital for Special Surgery

    New York, New York, 10021, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.