Could a blood injection boost shoulder surgery success?

NCT ID NCT07689383

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study tests whether adding platelet-rich plasma (PRP) — a concentrated solution made from a patient's own blood — to standard rotator cuff repair surgery improves healing. About 51 adults with confirmed rotator cuff tears who have not improved with physical therapy will receive either surgery alone or surgery plus PRP. Researchers will measure shoulder function, pain, and tendon healing on MRI up to one year after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
platelet-rich plasma (PRP)
What this could lead to
If it works, this could mean better healing and fewer repeat tears after rotator cuff surgery, potentially improving shoulder function and reducing pain.
What could go wrong
This is a small, early-phase study (51 people) and PRP may not provide significant benefit over surgery alone. There is also a risk of infection or reaction at the injection site.

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Conditions

The condition(s) this trial relates to.

Rotator Cuff Injuries rotator cuff syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • KAT General Hospital

    Kifissia, Attica, 14561, Greece

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