Which painkiller wins for shoulder surgery? a Head-to-Head test

NCT ID NCT07779473

Ongoing Symptom relief Sponsor: University of Thessaly Source: ClinicalTrials.gov ↗

First seen Aug 21, 2026 · Last updated Aug 21, 2026

Summary

This trial compares two pain medications, tramadol and tapentadol, to see which provides better pain relief after arthroscopic rotator cuff repair surgery. Adults aged 18-80 undergoing this elective shoulder surgery will receive one of the two drugs as part of a multimodal pain management plan. The study measures pain levels using a standard 0-10 scale after surgery, aiming to identify which drug offers more effective postoperative pain control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Two painkiller drugs, tramadol and tapentadol, given after surgery to manage pain.
What this could lead to: If one drug works better, it could lead to more effective pain management after rotator cuff surgery, potentially reducing chronic pain.
What could go wrong: This is a small trial, and results may not apply to everyone. Both drugs can cause side effects like nausea or dizziness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Pain, Postoperative rotator cuff syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHROSCOPIC ROTATOR CUFF REPAIR (ARCR) CHRONIC PAIN POSTOPERATIVE PAIN

Contacts and locations

Locations

Larissa University Hospital

Larissa, Thessaly, 41110, Greece

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