Can the right anesthesia cut Post-Surgery pain and opioid use?
NCT ID NCT04002271
First seen Aug 21, 2026 · Last updated Aug 21, 2026
Summary
This trial compares three common anesthesia techniques—spinal block, inhaled gas, and propofol intravenous anesthesia—for people undergoing robotic-assisted total knee replacement. The goal is to see which approach provides the best pain relief after surgery, reduces the need for strong painkillers, and supports faster recovery. Participants are randomly assigned to one of the three methods, and their pain levels and medication use are tracked during their hospital stay.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Three anesthesia techniques: spinal anesthesia, general anesthesia with inhaled gas, and general anesthesia with propofol (intravenous).
- What this could lead to
- If one technique proves superior, it could establish a standard for pain control after robotic knee replacement, reducing opioid use and improving recovery.
- What could go wrong
- The trial is early and results may not apply to all patients. Each anesthesia method carries inherent risks, and pain outcomes may vary widely.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Queen Mary Hospital
Hong Kong, Hong Kong
-
The University of Hong Kong
Hong Kong, Hong Kong
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a second nerve block double down on Post-Surgery pain relief?