Can a nerve stimulator outsmart a placebo for chronic pain?
NCT ID NCT07779733
First seen Aug 21, 2026 · Last updated Aug 21, 2026
Summary
This trial asks whether continuing BurstDR spinal cord stimulation—a therapy that uses an implanted device to send electrical pulses to the spine—actually relieves chronic pain better than a sham (inactive) stimulation. Adults who already have the device and have experienced good, stable pain relief for at least three months will receive both active and sham stimulation in random order, without knowing which is which. Each person serves as their own comparison, and the study tracks pain levels, satisfaction, sleep, mood, and daily activities to see if the active stimulation truly makes a difference.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- BurstDR spinal cord stimulation (a type of electrical nerve stimulation delivered via an implanted device)
- What this could lead to
- If active BurstDR proves better than sham, it would confirm that ongoing stimulation is what provides pain relief, supporting its continued use and possibly refining how it's delivered.
- What could go wrong
- This is a small, early-stage crossover study with only 28 participants. The sham may also provide some relief, and results may not apply to all chronic pain patients. Risks include discomfort or side effects from stimulation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital of Northern Sweden
Umeå, 90185, Sweden
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