Could a hormone patch boost shoulder surgery recovery?

NCT ID NCT06318403

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether estradiol patches can improve shoulder healing after rotator cuff repair in post-menopausal women. About 58 women will receive either an estradiol patch or a placebo patch for three months after surgery. The goal is to see if the hormone helps reduce pain, improve strength, and restore shoulder function better than surgery alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
estradiol (a form of estrogen) given as a skin patch
What this could lead to
If it works, this could point toward a simple hormone treatment to improve recovery and reduce pain after rotator cuff surgery in post-menopausal women.
What could go wrong
This is a very small, early-phase trial with only 58 participants. The results may not apply to all women, and the hormone patch could have side effects like skin irritation or hormone-related risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MENOPAUSE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Rotator Cuff Injuries rotator cuff syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.