Xijing Hospital

This early study tests whether stimulating a nerve in the lower back (sacral nerve stimulation) can safely help control symptoms of ulcerative colitis. It includes 15 adults with moderate-to-severe disease who have not responded to standard medications. The main goal is to see if…

This study tests whether the inhaled anesthetic desflurane is better than propofol at preventing major heart events like death, heart failure, or heart attack in adults undergoing coronary artery bypass surgery. About 3,560 participants will be randomly assigned to receive one of…

This early-phase trial tests whether combining cadonilimab with high-dose interferon before surgery can shrink tumors in people with stage III or IV melanoma. About 10 participants will receive the treatment and be monitored for side effects and tumor response. The goal is to gat…

This study compares a new dissolvable heart stent (Firesorb) to a standard metal stent in 2,000 people with coronary artery disease. The dissolvable stent is designed to support the artery temporarily and then disappear, potentially reducing long-term risks. The goal is to see if…

This study tests an experimental drug called picankibart in 60 adults with moderate-to-severe palmoplantar pustulosis, a chronic skin condition causing painful, pus-filled blisters on the palms and soles. Participants must have tried at least one standard treatment without succes…

This study tests a drug called meplazumab in 18 adults with coronary artery disease (narrowed heart arteries). The drug targets inflammation in artery plaques, which may help slow disease progression. Participants receive the drug or a placebo for several months, and doctors use …

This study tests if a low-protein diet (low in branched-chain amino acids) combined with an immunotherapy drug (anti-PD-1) is safe and effective for people with stage III melanoma. About 80 participants will receive the diet and drug before surgery. Researchers will monitor side …

This study tests a new immunotherapy drug (QL1706) combined with short cycles of chemotherapy for people with early-stage triple-negative breast cancer (TNBC), an aggressive type. About 30 participants will receive either QL1706 plus one chemo pair or another, to see if the combi…

This study is testing a new 3D-printed biodegradable mesh used during breast reconstruction after mastectomy for breast cancer. The mesh is designed to support the implant and help tissue heal, with the goal of improving cosmetic results and patient satisfaction. About 25 women a…

This study tests whether adding the drug serplulimab to standard chemotherapy before and after surgery helps people with advanced stomach or gastroesophageal junction cancer. About 116 adults will be randomly assigned to receive either the combination or chemotherapy alone. The m…

This study tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation can help people recover better after a stroke. Researchers will compare real stimulation to a sham (fake) treatment in 60 adults who recently had a clot-removal procedure.…

This study aims to develop a blood test that uses genetic material from tiny particles (exosomes) to predict whether prostate cancer has spread to the bones. Researchers will analyze blood samples from 1,000 men with newly diagnosed prostate cancer and compare the results to PSMA…

This study looks at whether taking a PSMA PET scan 2-3 hours after the injection (instead of the usual 1 hour) can better find aggressive prostate cancer in men who haven't been treated yet. About 1,000 men with suspected prostate cancer will get both scans, and doctors will comp…

This study aims to see if a special PET scan (68Ga-PSMA) is better than standard CT scans at finding where kidney cancer has spread in the body. About 300 adults with advanced kidney cancer will get both scans, and doctors will compare the results. If the PET scan proves more acc…

This study is testing a new blood test that looks for tiny genetic particles (exoRNA) to find clinically significant prostate cancer. The goal is to see if this test can accurately diagnose the disease and reduce the need for invasive biopsies. The study will involve 1700 men wit…

This study tests whether a device that sends mild electrical pulses through the skin (TENS) can safely reduce pain and improve daily function in adults with chronic low back pain. Forty participants will receive TENS treatment five times a week for four weeks. Researchers will me…

This study tests a non-invasive magnetic stimulation technique on the cerebellum to see if it can improve cognitive function and quality of life in people with mild Alzheimer's disease. Researchers will enroll 100 adults aged 50-85 who have mild Alzheimer's and stable medication.…

This study tests a new pill, ivarmacitinib, in 60 adults with palmoplantar pustulosis (PPP), a chronic skin condition causing painful blisters on hands and feet. Participants take one 4mg pill daily for 12 weeks. Researchers will measure how well it reduces symptoms and track sid…

This study tests whether a numbing injection near the neck (stellate ganglion block) given before coronary artery bypass surgery can lower the chance of developing a fast, irregular heartbeat (atrial fibrillation) after the operation. About 60 adults having bypass surgery will be…

This early-stage study tests whether a medicine made from horse chestnut extract (sodium aescinate) can safely reduce pain in adults with long-term low back pain. About 40 people will take either the medicine or a placebo pill for a set time, and researchers will measure changes …

This study looks at whether a PSMA PET scan, taken before any treatment, can help predict how prostate cancer will progress in newly diagnosed patients. Researchers will follow 1,000 men for at least 2 years to see if the scan results can forecast cancer growth or spread. The goa…

This study enrolls 600 people – both heart disease patients who have had a stent procedure and healthcare providers – to understand how they rank the seriousness of different health events like heart attack, stroke, or bleeding. The goal is to improve how clinical trials measure …

This study surveys 600 people—including heart disease patients and their healthcare providers—to understand their preferences between two treatments for blocked arteries: permanent metal stents (DES) or drug-coated balloons (DCB) that leave no metal behind. The goal is to find ou…

This study looks at whether changes in DNA markers in the blood can show how well esophageal cancer treatment is working. Researchers will compare these markers to standard scans and tumor tests. The goal is to find a simpler, less invasive way to monitor the disease and guide tr…

This study follows 1500 adults having planned heart surgery to learn why some become confused or delirious afterward. Researchers will track patients before and after surgery to find risk factors and see how delirium affects recovery over time. The goal is to better predict and p…

This study looks at whether the anesthetic propofol can lower the chance of confusion (delirium) after surgery in diabetic patients aged 60 and older. About 450 people having non-cardiac surgery will be randomly assigned to receive either propofol or sevoflurane during their oper…

This study is looking at blood samples from 200 people with melanoma to find markers that can help doctors track how well treatment is working. Participants will give blood before and during standard immunotherapy, and have scans every 12 weeks. The goal is to develop a simple bl…

This study looks at why many people with ulcerative colitis have trouble sleeping and how that affects their disease. Researchers will track sleep quality, gut bacteria, and nerve activity in 152 patients. The goal is to understand the connection between the gut and brain to impr…

This study looks at whether a special type of PET scan (PSMA PET) can better track how well prostate cancer treatment is working. It involves 110 men with newly diagnosed, aggressive prostate cancer. They will get a PSMA PET scan before treatment and another one after treatment t…

This study looks at how taking multiple medications affects the health of elderly people with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will survey 2000 patients aged 65 and older in Shaanxi Province, China, over two years. The goal is to…