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Could a magnetic helmet boost memory in Alzheimer's?

NCT ID NCT06669182

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if a gentle magnetic pulse to the back of the brain (cerebellum) can help people with mild Alzheimer's disease think more clearly and feel better day-to-day. About 100 adults aged 50-85 will receive either real or fake stimulation over three months. The goal is to see if this safe, non-invasive treatment can slow down memory loss and improve quality of life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age: 50-85 years old 2. Meet the core clinical criteria of NIA-AA for possible Alzheimer's disease dementia, and PET or cerebrospinal fluid markers show elevated p-tau and decreased A β (1-42) 3. MMSE score ranges from 18-26 points; CDR score 0.5-1 points 4. The patient has received treatment with acetylcholinesterase inhibitors (AChEI), NMDA receptor antagonists, or mannequine therapy, and the current dosing regimen has remained stable for the 12 weeks prior to baseline assessment 5. At least one adult caregiver 6. The patient or legal guardian voluntarily signs the informed consent form Exclusion Criteria: 1. Neurodegenerative disorders other than AD. 2. Significant intracranial focal or vascular pathology seen on brain MRI scan 3. History of seizure (with the exception of febrile seizures in childhood) 4. Any of the following psychotic disorders (DSM IV-TR criteria): * Major depressive disorder (current) * Schizophrenia * Other psychotic disorders, bipolar disorder, or substance related disorders (within the past 5 years) 5. GDS score ≥ 8 points in baseline assessment 6. Cerebrovascular disease, severe infection, malignant tumor, or severe dysfunction of organs such as heart, liver, and kidney. 7. Pregnant or lactating women 8. Contraindications for TMS or MRI, metal or implanted devices in the body (such as pacemakers, deep brain stimulators). 9. Participate in AD related clinical trials within 6 months prior to research registration

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Tangdu Hospital of Air Force Military Medical University

    RECRUITING

    Xi'an, Shannxi, China

  • The First Affiliated Hospital of Xi'an Medical University

    RECRUITING

    Xi'an, Shannxi, China

  • The Third Hospital of Xi'an

    RECRUITING

    Xi'an, Shannxi, China

  • Xijing Hospital of Air Force Military Medical University

    RECRUITING

    Xi'an, Shaanxi, 710032, China

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