New PET scan could outshine CT for kidney cancer staging
NCT ID NCT04987086
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a special PET scan (68Ga-PSMA) with standard CT scans to see which better detects where kidney cancer has spread in 300 adults with advanced disease. Participants will receive both scans, and doctors will check if the PET scan changes treatment plans. The goal is to improve accuracy and help guide better care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2021
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 2017 AJCC renal cell carcinoma TNM stage III, IV lesions; * In contrast-enhanced CT staging, suspicious metastases were found; * There were no known peripheral or central venous problems; * 68Ga PSMA PET / CT imaging can be performed within 6 weeks after the diagnosis of renal cell carcinoma; * Signed the informed consent form of voluntary participation in clinical trials. Exclusion Criteria: * Age ≤ 18 years old; * Can't stand lying flat in PET / CT examination; * There are contraindications for 68Ga PSMA ligands; * In the past two years, there was a history of other malignant tumors, or according to the doctor's research judgment, complications may occur and affect the normal operation of the test; * Renal function is impaired or hemodialysis is in progress.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
9 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Affiliated Hospital of Yan'an University
RECRUITINGYan’an, Shaanxi, China
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General Hospital of Ningxia Medical University
RECRUITINGYinchuan, Ningxia, China
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Qinghai University Affiliated Hospital
RECRUITINGXining, Qinghai, China
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Shaanxi Provincial People's Hospital
RECRUITINGXi'an, Shaanxi, China
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The First Hospital of Lanzhou University
RECRUITINGLanzhou, Gansu, China
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The Second Affiliated Hospital of Shaanxi University of Chinese Medicine
RECRUITINGXianyang, Shaanxi, China
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Weinan Central Hospital
RECRUITINGWeinan, Shaanxi, China
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Xijing 986 Hospital
RECRUITINGXi'an, Shaanxi, China
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Xijing Hospital
RECRUITINGXi'an, Shaan'xi, 710032, China
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Other studies related to the condition(s) this trial covers.
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- Smart blood pressure monitoring may shield kidneys during robotic surgery
- Can a new drug target Hard-to-Treat kidney and ovarian cancers?
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