Xijing Hospital

This study tests a combination of three drugs (neratinib, fulvestrant, and eribulin) in 35 women with a specific type of advanced breast cancer (HR+/HER2+) that no longer responds to the drug trastuzumab deruxtecan. The goal is to see if this new mix can shrink tumors or slow the…

This study tests whether removing the central mole (nevus) in people with halo nevus and vitiligo leads to better skin color restoration than using medication alone. Sixty participants aged 6 to 45 will be randomly assigned to either have the mole removed plus medication, or rece…

This study tests whether adding the targeted drug zanidatamab to standard chemotherapy before surgery can shrink tumors more effectively in people with HER2-positive stomach or gastroesophageal junction cancer. About 30 adults with stage II/III cancer will receive the combination…

This study tests whether giving two drugs—serplulimab and trastuzumab rezetecan—before surgery can completely eliminate triple-negative breast cancer in 84 women. Participants will receive the combination as neoadjuvant therapy, and the main goal is to see how many have no cancer…

This early-stage study tests a new treatment called S103 (BCMA-CAR T cells) for people with progressive or hard-to-treat multiple sclerosis (MS). The main goal is to check if the treatment is safe and to find the right dose. Only 9 adults will take part, and the study is not yet …

This study tests whether exosomes from umbilical cord stem cells can safely help restore skin color in adults with vitiligo. It includes 96 people with active or stable vitiligo, comparing the exosome treatment plus standard therapy to standard therapy alone. The goal is to see i…

This study looks at whether testing stool samples for certain markers can help find stomach and colon cancers early. About 5,000 adults scheduled for a routine scope will provide a stool sample and answer health questions. Researchers will then check how accurate the stool test i…

This study tests two different medicines given at the end of colorectal surgery to reverse muscle relaxants. The goal is to see which one helps the bowel start working again sooner. 560 adults having planned colorectal surgery will be randomly assigned to receive either sugammade…

This study tests a new, non-invasive brain stimulation method called temporal interference (TI) to reduce seizures in people with drug-resistant temporal lobe epilepsy. Researchers will treat 30 adults for 5 days and track seizure frequency for one to two months. The goal is to s…

This study tests whether a gentle, non-invasive electrical stimulation on specific points on the hands can help people with severe brain injury improve their level of consciousness. The treatment is based on traditional Chinese medicine but uses modern technology. The study will …

This study tests a new painkiller called oliceridine fumarate in 428 adults having lumbar spine surgery. The goal is to see if it controls pain as well as standard opioids but with fewer side effects like constipation and breathing problems. Participants will be randomly assigned…

This study looks at whether giving tube feedings at set times (intermittent) versus nonstop (continuous) helps people with severe stroke live longer and recover better. About 60 patients will be randomly assigned to one of the two feeding methods. Researchers will track survival,…

This study will test if a non-invasive device called Electrical Impedance Tomography (EIT) can safely and accurately measure how well the brain controls its blood flow in critically ill patients. Currently, doctors must insert a probe into the skull to get this information, which…

This study aims to create a model using 12 immune markers in the blood to predict when vitiligo will worsen and how well treatment will work. Researchers will enroll 125 adults with vitiligo and a healthy comparison group. The goal is to replace guesswork with objective lab resul…

This study looks at whether a blue dye alone can safely find cancer in lymph nodes after chemotherapy in women with breast cancer that had spread to the lymph nodes. About 240 women will get the dye injection during surgery, followed by standard lymph node removal. The goal is to…

This study follows 1,630 people with a small, low-risk thyroid cancer to see which of three approaches works best: surgery, heat ablation (a minimally invasive procedure), or active surveillance (monitoring without immediate treatment). The goal is to compare safety, quality of l…

This study watches how the brain heals in the first week after a stroke clot is removed. It involves 180 adults who had a stroke and successful treatment. Researchers use brain scans and electrical readings to track recovery and predict long-term outcomes, which could lead to bet…

This study looks at whether the way you sleep before heart surgery is connected to your risk of confusion (delirium) and kidney injury after the operation. Researchers will track 549 adults having planned heart surgery with a heart-lung machine. The goal is to better understand t…