Stool sample screening could revolutionize digestive cancer detection
NCT ID NCT07600125
First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times
Summary
This study aims to see if testing stool samples for multiple markers can accurately screen for stomach and colorectal cancers. About 5,000 adults scheduled for endoscopy will provide a stool sample before the procedure and be followed for two years. The goal is to develop a non-invasive screening tool that could catch these cancers earlier.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study will enroll individuals aged 18 and older who are scheduled to undergo gastrointestinal endoscopy and are willing to participate in the screening.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Participants must be at least 18 years of age at the time of enrollment; 2. Participants must be scheduled to undergo gastroscopy and colonoscopy; 3. Participants must agree to undergo a two-year follow-up as outlined in the protocol; 4. Participants must be willing to participate and sign an informed consent form. Exclusion Criteria: 1. Have undergone gastrointestinal endoscopy screening within the past year; 2. History of any type of gastrointestinal malignancy; 3. Concurrent severe medical conditions that reduce the benefits of screening, such as severe pulmonary disease, kidney disease, liver disease, cardiovascular and cerebrovascular diseases, and hematological disorders; 4. Other situations where a physician determines that endoscopic screening poses excessive risk (e.g., hemodynamic instability) or offers no benefit (e.g., short life expectancy); 5. Pregnant or breastfeeding women.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
13 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cao County People's Hospital
RECRUITINGHeze, China
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Central Theater Command General Hospital
RECRUITINGWuhan, China
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Gaoyao District People's Hospital, Zhaoqing City, Guangdong Province
RECRUITINGZhaoqing, China
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Hongxing Hospital of the 13th Division, Xinjiang Production and Construction Corps
RECRUITINGHami, China
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Huoqiu County People's Hospital
RECRUITINGLiu‘an, China
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PetroChina Central Hospital, Hebei
RECRUITINGLangfang, China
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Qingdao Municipal Hospital
RECRUITINGQingdao, China
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The 960th Hospital of the Joint Support Force of the People's Liberation Army of China
RECRUITINGJinan, China
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The First Affiliated Hospital of Air Force Military Medical University
RECRUITINGXi'an, Shaanxi, 710032, China
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The First Affiliated Hospital of Dalian Medical University
RECRUITINGDalian, China
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Wuwei Cancer Hospital of Gansu Province
RECRUITINGWuwei, China
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Wuxi People's Hospital
RECRUITINGWuxi, China
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Zhaoqing First People's Hospital, Guangdong Province
RECRUITINGZhaoqing, China
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