Xijing Hospital

This phase II trial tests whether giving a combination of inetetamab, pyrotinib, and nab-paclitaxel before surgery can eliminate cancer in women with HER2-positive early or locally advanced breast cancer. Participants receive four cycles of the drugs, then undergo surgery. The ma…

This trial investigates whether the antibiotic minocycline can reduce brain injury in people with acute ischemic stroke who undergo mechanical thrombectomy (clot removal). Minocycline may protect the blood-brain barrier and limit damage from restored blood flow. The study enrolls…

This study tests a new, less invasive procedure called PIMSRA for children with obstructive hypertrophic cardiomyopathy, a condition where the heart muscle is too thick and blocks blood flow. The procedure uses a needle guided by ultrasound to deliver radiofrequency energy to the…

This study looked at whether giving fluids (colloids or crystalloids) before general anesthesia can prevent low blood pressure and reduce complications within 30 days after non-cardiac surgery. Over 2,000 adults having elective surgery took part. The goal was to see if this simpl…

This study tested a new drug combination (fluzoparib plus chemotherapy) given before surgery to 28 women with a specific type of early breast cancer (HR+/HER2- with HRD). The goal was to see if it could shrink tumors more effectively. The treatment was given over 8 cycles, and th…

This study looked at whether a drug-coated balloon (DCB) can safely treat blocked heart arteries, possibly avoiding the need for a permanent stent. Researchers followed 2487 patients who received the balloon instead of a stent. The goal was to see how well the balloon prevents he…

This study tested a combination of the immunotherapy drug tislelizumab and chemotherapy (XELOX) given before surgery to 28 people with locally advanced stomach or gastroesophageal junction cancer. The goal was to see if this approach could shrink tumors more effectively and be sa…

This trial tests whether a sedative nasal spray, given the night before and just before cardiac surgery, can reduce the chance of postoperative delirium—a state of confusion that can complicate recovery. The idea is that improving sleep before surgery may protect the brain. About…

This study looks at whether giving L-Arginine soon after heart surgery that uses a heart-lung machine can lower the chance of acute kidney injury. It will follow over 5,000 adults in the intensive care unit after their operation. The goal is to see if this simple amino acid might…

Researchers test whether repetitive transcranial magnetic stimulation (rTMS) can reduce depression and anhedonia, the inability to feel pleasure, in teenagers. The trial enrolls 88 adolescents with major depressive disorder who score high on measures of depression and anhedonia. …

This study compares two common anesthetics—propofol and sevoflurane—to see which one causes less confusion (delirium) after surgery in older diabetic patients. Researchers will enroll 450 people aged 60 and older undergoing non-cardiac surgery. The goal is to find the best anesth…

This study tests whether giving a nerve block (stellate ganglion block) before coronary artery bypass grafting (CABG) can reduce the chance of developing atrial fibrillation, a common irregular heartbeat after surgery. About 60 adults having CABG will be randomly assigned to rece…

This study tests different ways of stimulating specific points on the hands (called Jing-Well points) to see if they can help people with disorders of consciousness after a severe brain injury. The trial involves 60 adults aged 18-80 who have been in a vegetative or minimally con…

This study looked at 562 adults having minimally invasive heart surgery to see if adding a long-acting steroid (dexamethasone palmitate) to a nerve block could prevent chronic pain better than a standard steroid. Participants received a one-time injection followed by a continuous…

This study tested a personalized form of brain stimulation called iTBS for people with major depression. Researchers used MRI scans to target specific brain areas in 68 participants. The goal was to see if this tailored approach could improve depression symptoms more than a sham …

This study tested a personalized form of transcranial magnetic stimulation (TMS) to treat emotional blunting—a common symptom where people feel numb or disconnected—in 80 adults with depression. Researchers used brain imaging to target the stimulation precisely. The goal was to s…

This study looks at whether post-traumatic stress disorder (PTSD) in surgeons and anesthesiologists is linked to higher rates of complications in the patients they operate on. Researchers will screen surgical staff for PTSD using questionnaires and then track the recovery of thei…

This study looks at whether the way you sleep before heart surgery is connected to problems like confusion (delirium) or kidney damage after the operation. Researchers will track 549 adults having planned heart surgery with a heart-lung machine. The goal is to find patterns that …

This study looked at 20 adults with and without kidney stones to find differences in blood and urine chemicals. Researchers measured neurotransmitters and gut bacteria byproducts to understand how metabolism may contribute to stone formation. The goal was to identify early warnin…

This study looked back at the records of 471 women who had breast cancer surgery with immediate implant reconstruction. It compared a newer method using a tiny camera through small cuts (endoscopic) to the traditional method with a larger cut. The goal was to see which approach l…

This completed study looked at 300 liver transplant cases to understand why donor livers with fatty liver disease are more likely to be injured after transplantation. Researchers compared genetic activity in archived tissue samples from 50 cases, using advanced techniques to iden…

This study looks back at 700 patients who had endoscopic treatment for gastrointestinal submucosal tumors at Xijing Hospital. Researchers want to know how often the tumors are completely removed, what complications occur, and whether the tumors come back over time. The goal is to…

This study analyzed blood and tumor tissue samples from 28 people with stomach cancer to find biological markers that predict how well immunotherapy (tislelizumab) combined with chemotherapy works before surgery. The goal was to build a model that uses RNA and other factors to fo…