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Can a safer anesthetic drug prevent Post-Surgery confusion in elderly diabetics?

NCT ID NCT06788743

First seen Jan 10, 2026 · Last updated Jun 23, 2026 · Updated 24 times

Summary

This study compares two common anesthetics—propofol and sevoflurane—to see which one causes less confusion (delirium) after surgery in older adults with diabetes. Researchers will enroll 450 patients aged 60 and older undergoing major non-cardiac surgery. The goal is to find the best anesthesia approach to improve recovery and reduce risks for this vulnerable group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Air Force Medical University

    RECRUITING

    Xi’an, Shanxi, 710032, China

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

propofol and sevoflurane (anesthetic drugs)

What this could lead to

If propofol works better, it could offer a safer anesthesia choice for elderly diabetic patients, reducing confusion after surgery.

What could go wrong

This is a mid-sized trial, not yet proven. Results may not apply to all patients, and both drugs have known side effects like low blood pressure or breathing issues.

Conditions

The condition(s) this trial relates to.

diabetes mellitus Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.