University Of Kansas Medical Center

This pilot study tested a new way of giving radiation for early-stage prostate cancer using fewer, stronger doses (ultra-hypofractionation). The main goal was to see if this approach causes less urinary side effects than standard radiation. The study enrolled 13 men with low-risk…

This study tested whether the drug megestrol can help children aged 9 months to 9 years who rely on feeding tubes learn to eat by mouth. About 70 children took either megestrol or a placebo as part of a 24-week feeding program. The main goal was to see if more children could get …

This study tested a new approach for people with advanced melanoma that cannot be removed by surgery or has spread. Doctors used a lower dose of two chemotherapy drugs (fludarabine and cyclophosphamide) to prepare the body, then infused the patient's own tumor-fighting immune cel…

This early-stage study tested whether losartan, a blood pressure medication, could help clear mucus from the lungs of adults with cystic fibrosis who are not eligible for standard CFTR therapies. Thirteen participants took losartan for over 12 weeks. The goal was to see if it imp…

This study tested a web-based version of a diabetes self-management program called eDECIDE for African Americans with type 2 diabetes. The program teaches problem-solving skills to handle daily challenges of living with diabetes. Researchers compared eDECIDE to the traditional in…

This early-stage study tested a treatment made from umbilical cord stem cells for people with a serious condition called graft-versus-host disease (GVHD), which can happen after a bone marrow or stem cell transplant. The study included 24 adults aged 18 to 75. Researchers gave tw…

This study tested whether two types of intermittent fasting (eating only at certain times or on certain days) can help people with type 2 diabetes control their blood sugar and possibly achieve remission. 57 adults with type 2 diabetes participated in a year-long lifestyle progra…

This study tested a program called eMOMS that combines breastfeeding support with a diabetes prevention plan. It was designed for pregnant women who were overweight or had obesity. The goal was to see if the program could help them lose weight after giving birth and breastfeed lo…

This study tested a long-lasting painkiller called liposomal bupivacaine (Exparel) in 19 people having hernia repair surgery. The goal was to see if it improves pain control and patient satisfaction after the operation. Researchers measured how satisfied patients were with their …

This study tested a 6-week sleep program in 200 older adults (ages 60-85) with insomnia to see if it improves thinking, memory, and attention. A small group also had brain scans to check for changes in amyloid plaque, a hallmark of Alzheimer's disease. The goal was to understand …

This study tested whether a weight loss program before total knee replacement helps people with obesity have better outcomes. 24 adults aged 50-75 with a BMI between 35 and 40 were randomly assigned to either a 3-month very low-calorie diet and exercise program before surgery, fo…

This study tested whether a long-acting numbing medicine (liposomal bupivacaine) can better control pain and reduce the need for opioid painkillers after skin graft surgery. 74 burn patients with small injuries took part. Researchers compared pain scores and opioid use between th…

This study tested whether a specialized swim program (Sensory Enhanced Aquatics) helps autistic children ages 5-9 learn swimming and water safety skills better than standard lessons. 51 children participated in 16 half-hour lessons. Researchers measured skills before and after to…

This study looked at whether a program combining yoga and support groups could help reduce stress for people caring for young adults with intellectual and developmental disabilities (IDD). Twenty caregivers took part. The goal was to see if the program was practical and if it hel…

This study tested whether stem cells taken from a person's own fat and injected into their forearm and thigh muscles are safe for people with Inclusion Body Myositis, a rare muscle-weakening disease. Nine adults took part, each receiving injections on one side of the body. The ma…

This pilot study tested a text-based reward system to help 20 adults stick with their smoking cessation plan. Participants received texts encouraging them to complete quitline counseling calls and take their medication (varenicline). The goal was to see if this approach was feasi…

This study looked at whether two special diets—the ketogenic diet and the Therapeutic Lifestyles Changes diet—could help improve thinking and memory in people with Alzheimer's disease. Researchers measured changes in cognitive performance over three months in 84 adults aged 50 to…

This study tested whether singing and vocal exercises can improve lung function in people with COPD, a chronic lung disease that makes breathing difficult. Five adults with COPD took part in virtual singing sessions twice a week for 4 weeks. Researchers measured air trapping in t…

This study compared two types of lasers (SOLTIVE Thulium and Ho:YAG) used to break up kidney stones during surgery. 100 adults with a single stone smaller than 2 cm took part. The goal was to see if the newer laser works faster and clears stones just as well as the standard one.

This study looked at whether doing kangaroo care (skin-to-skin contact) right in the operating room after a C-section helps mothers feel more satisfied and have less pain. 158 mothers with a single, full-term baby took part. Researchers measured satisfaction, pain levels, and bab…

This study tested whether MRI can detect lung disease in people with scleroderma, a condition that can cause scarring in the lungs. Researchers compared MRI images with standard CT scans in 25 adults. The goal was to see if MRI could be a safe, radiation-free way to screen for an…

This study looked at whether having a doula—a trained birth supporter—helps Black pregnant people feel more heard and respected by their doctors. Thirty participants completed surveys about their communication and care experiences. The goal was to learn how doula-enhanced care mi…

This study aimed to find out if certain patient traits or risk factors can predict who will develop chronic pain after lower back surgery. Researchers studied 158 adults who had lumbar spine surgery, measuring pain severity, disability, and other health factors. The goal was to b…

This study looked at 50 people with and without low back pain to test a new tool that measures how much pressure physical therapists apply during spinal mobilization. Participants received standard back pressure techniques and had their pain thresholds and muscle activity tested.…

This study used brain scans (fMRI) to understand how people make decisions about drinking alcohol in everyday situations, especially when they have important things to do the next day. Researchers looked at 52 heavy drinkers to see how their brains reacted to different scenarios.…

This study tested whether a 12-week online dance program is practical and enjoyable for young adults with Down Syndrome. Twenty participants took two 35-minute group dance classes each week. Researchers measured attendance, safety, and changes in fitness and thinking skills. The …

This study tested how different nicotine concentrations in e-cigarettes influence puffing behavior and switching from cigarettes. 52 Black and White smokers who wanted to try e-cigarettes participated. Researchers measured inhaled volume and tracked whether participants switched …

This study tested a special MRI technique using inhaled xenon gas to see how well the lungs exchange gas in people with pulmonary arterial hypertension (PAH). Ten adults with PAH had four MRI scans over 18 weeks while starting or continuing treatment. The goal was to find new ima…

This study tested a new approach to help older Latinos with dementia get better care. Researchers trained primary care doctors in Kansas City to improve their skills in detecting dementia and referring patients to a Health Navigator. The Navigator then provided support and connec…

This study tested a sleep health program in 30 adults aged 45-64 to see if it improves sleep and might help prevent Alzheimer's disease later. Participants learned about sleep habits and wore a wrist monitor for a week. The goal was to see if the program was easy to use and actua…

This study used a special type of MRI to look at lung function in 42 adults recovering from COVID-19. Researchers measured how well the lungs were working at the start and again after 6 months. The goal was to understand lung damage from mild to severe COVID-19, not to test a tre…

This study tested whether an electronic alert in medical records could help doctors refer patients with fatty liver disease (NASH) to liver specialists. It involved 30 doctors from internal medicine, family medicine, and endocrinology. The goal was to see if the alert increased a…

This study looked back at medical records of 45 women whose copper IUD broke when being taken out, requiring a special camera procedure (hysteroscopy) to remove the pieces. The goal was to find out what factors might make an IUD more likely to break. The study did not test any ne…

This study looked at whether older African Americans (55+) with heart disease risk factors could follow a special diet called MIND+SOUL. The diet combines brain-healthy foods with soul food traditions. Researchers measured how many people stuck with the diet and checked changes i…

This study tested a program called KanSurvive-ECHO to help rural primary care clinics provide better follow-up care for cancer survivors. Researchers worked with 15 clinics to improve tasks like scheduling cancer screenings, checking for distress, and tracking weight and tobacco …

This study looked at how different types of exercise affect fitness and blood vessel health in people who have had a stroke. 59 adults who had a stroke 6 months to 15 years ago took part. They used a seated stepper that moves arms and legs to compare high-intensity interval train…