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Weight loss before knee surgery shows promise in small trial

NCT ID NCT05853497

First seen Oct 31, 2025 · Last updated May 23, 2026 · Updated 31 times

Summary

This study tested whether a weight loss program before total knee replacement helps people with obesity have better outcomes. 24 adults aged 50-75 with a BMI between 35 and 40 were randomly assigned to either a 3-month very low-calorie diet and exercise program before surgery, followed by a maintenance diet after, or to standard care. The goal was to see if the program was feasible and could reduce pain and improve knee function.

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Contacts and locations

Locations

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

Conditions

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