University Of Kansas Medical Center

This phase 2 trial is testing whether adding an investigational drug called ivonescimab to standard chemotherapy before surgery can improve outcomes for people with triple-negative breast cancer. Ivonescimab is a bispecific antibody that works in two ways: it helps the immune sys…

This pilot study tests whether offering rewards for taking smoking cessation medication and completing counseling calls helps people quit smoking. Participants receive varenicline and referrals to a state quitline, with some also getting incentives tracked by a smart pill dispens…

This study looks at whether people with advanced breast cancer that has spread to lymph nodes can safely have a less extensive armpit surgery after chemotherapy. Instead of removing many lymph nodes, doctors will remove only a few and then give radiation. The goal is to see if th…

This trial explores whether starting cognitive behavioral therapy for insomnia (CBT-I) early—before a stem cell transplant—can reduce insomnia and fatigue and improve quality of life. Adults planning a transplant who have sleep problems will be randomly assigned to either six wee…

This study tests whether using a breast pump for nipple stimulation can safely start labor in pregnant women. The gentle suction may trigger the body's own oxytocin to encourage contractions. Researchers will measure total labor time and compare it to standard methods. The goal i…

This study looks at whether a well-formulated ketogenic diet can reduce pain and improve thinking in adults with osteoarthritis and mild cognitive impairment. Ten participants will follow a supervised low-carb, high-fat diet for a period, with before-and-after tests for pain, phy…

This study looks at whether low-volume high-intensity interval training (HIIT) on a recumbent stepper is safe and doable for people recovering from a stroke in a hospital rehab setting. Fifteen participants will try a 10-minute HIIT session, and researchers will track any side ef…

This pilot study tests whether 10 sessions of low-fidelity driving simulator training can improve driving performance, confidence, and thinking skills in people with Parkinson's disease. 36 participants will be randomly assigned to either the simulator training or a waitlist grou…

This study tests whether combining robot-assisted walking training with mild electrical stimulation of the spinal cord can help people who have had a stroke and cannot walk. Twenty chronic stroke survivors will receive 24 sessions of this combined therapy. The goal is to see if t…

This study is testing a 6-session family program called NOURISH-ALL for children ages 2-12 with acute lymphoblastic leukemia (ALL) and their caregivers. The program focuses on healthy eating, physical activity, and reducing family stress during early treatment phases. The main go…

This study will adapt and test an online communication training program called CHATO for nursing home staff who care for people with dementia. The goal is to improve how staff interact with residents, which may reduce behavioral symptoms like agitation or rejection of care. Resea…

This study collects blood and tissue samples from 110 adults with advanced lung, head and neck, or mesothelioma cancer. The samples are stored in a biobank to help scientists study cancer genes and find better ways to predict treatment outcomes. Participants do not receive any ex…