University Of California, Los Angeles

This study tested different ways to help teenagers complete the HPV vaccine series at community health centers serving low-income families. Researchers compared parent reminders (by mail and text), clinic system changes, and a combination of both against usual care. Over 17,000 t…

This study tested whether cannabidiol (CBD) can help people with opioid use disorder reduce cravings and prevent relapse. 35 adults already taking standard medications (buprenorphine or methadone) were randomly given either CBD or a placebo for 28 days. Researchers measured safet…

This study looked at whether visits from a parish nurse can help people with high blood pressure get it under control. About 100 adults from church health fairs in Los Angeles took part. Half were assigned to see a parish nurse, and the other half went to their regular doctor. Af…

This study tested whether a daily supplement called COMP-4 can improve blood vessel function and reduce signs of aging in 32 healthy adults aged 18-39. Participants took the supplement for 14 days, and researchers used ultrasound to measure blood vessel dilation and blood tests t…

This study looked at a new program called the Next Day Clinic (NDC) at UCLA. Instead of admitting certain patients from the emergency room to the hospital, the clinic sends them home and sees them the next day. The goal is to keep people out of the hospital when it's safe, improv…

This study tested whether a mindfulness program could help people with high blood pressure better follow their medication, diet, and exercise plans. 36 adults who struggled with these habits took part. The goal was to see if mindfulness training improves adherence and lowers bloo…

This early-stage study tested whether giving rituximab before standard methotrexate-pegloticase therapy could help people with severe tophaceous gout who had stopped responding to pegloticase. Only 2 participants were enrolled. The main goal was to check safety and see if the tre…

This study looked at whether using an antibacterial mouthwash every day could lower the chance of getting gonorrhea in the throat among men at high risk, including those with and without HIV. Researchers compared the antibacterial mouthwash to a placebo (fake) mouthwash to see if…

This study tested whether a smartphone app (GeoPassport) plus incentives and peer mentors could help men who have sex with men and transgender women leaving jail get HIV prevention services like PrEP and testing. 233 participants were split into two groups: one got routine case m…

This study tested whether a dietary supplement called Mito-MES could prevent healthy adults from developing severe viral infections, like COVID-19, after being exposed to a sick person at home. 80 adults who had close contact with someone with respiratory symptoms took the supple…

This study tested whether a program designed for Latino men who have sex with men could help them start taking PrEP, a daily pill that prevents HIV. 105 participants joined the study. The program was tailored to their culture and needs. The goal was to see if the program was easy…

This study tested a diabetes prevention program designed for college students facing challenges like food and financial insecurity. About 80 UCLA undergraduates at high risk for type 2 diabetes took part. The program included 19 group sessions focused on healthy habits and weight…

This study tested a new type of therapy called reminder-focused positive psychiatry (RFPP) for teenagers who have both ADHD and PTSD. The goal was to see if it was acceptable and feasible to use, and if it could help reduce symptoms and improve well-being. Eleven teens took part …

This study tested whether 6 months of weekly Kundalini yoga classes with daily meditation could improve memory and thinking in 81 older adults with mild cognitive impairment, compared to weekly memory training classes with daily homework. The goal was to see if these activities h…

This study tested a 15-session exercise camp for children aged 5 to 18 with spastic cerebral palsy. The goal was to see if the program could improve leg movement, walking, running, and stair climbing. All 23 participants attended the camp and did home exercises afterward. Researc…

This study tested a sleep improvement program designed for both Alzheimer's patients and the people who care for them. 60 pairs (patient and caregiver) joined the study. The goal was to see if a tailored program could help both get better sleep and reduce related health problems.

This study tested a 9-week kindness-focused mindfulness program for teens aged 12-17 with anxiety or depression. Half of the parents also took the program to see if it added extra benefit. The goal was to see if mindfulness could reduce symptoms and improve well-being.

This study tested whether eating two ounces of walnuts each day could improve sperm count, movement, and shape in men with fertility issues. 80 men took part, comparing walnuts to a standard multivitamin. The goal was to see if this simple diet change could help with natural or a…

This early study tested whether combining psilocybin (the active ingredient in magic mushrooms) with cognitive behavioral therapy is safe and helpful for people with major depression. Sixteen adults received two doses of psilocybin along with 12 therapy sessions. The goal was to …

This study tested whether eating 2 ounces of walnuts daily for 12 weeks could improve memory and reduce brain fog in adults over 40 with Long-COVID. 31 participants were randomly assigned to either add walnuts to their usual diet or continue their normal care. The goal was to see…

This study tested whether adding behavioral skills training to standard job support helps people with schizophrenia keep a job longer. 107 adults took part. The main goal was to see if the extra training increased the total number of weeks worked.

This study looked at whether a program called SKY Recovery, which teaches breathing and meditation, can help people recovering from substance use disorder. About 100 people in a residential treatment center took part. The program included a 5-day workshop and weekly follow-ups. R…

This study looked at whether combining internet-based cognitive behavioral therapy (iCBT) with transcranial magnetic stimulation (TMS) works better than TMS alone for people with major depressive disorder. Forty adults received either TMS plus iCBT or TMS alone. The goal was to s…

This study tested whether adding online cognitive behavioral therapy (CBT) to a gentle 12-week benzodiazepine taper helps patients with anxiety who also take prescription opioids. 42 adults participated, receiving either CBT or health education alongside the taper. The goal was t…

This study tested a personalized, play-based program for 2-3 year olds with autism. The program, called JASPER, was delivered by trained teaching assistants in community preschools. The goal was to see if adjusting the type and amount of play therapy based on each child's progres…

This study tested a non-invasive device that gently stimulates a nerve in the face (trigeminal nerve) to see if it can reduce ADHD symptoms in children aged 7 to 12. Over 200 children received either the active device or a sham (fake) device for 4 weeks. The goal was to measure c…

This study tested a new, non-invasive technique called Low-Intensity Focused Ultrasound Pulsation (LIFUP) to see if it can improve motor symptoms in people with Parkinson's disease. 31 participants received the ultrasound while their brain activity was monitored with an MRI. The …

This study looked at behavior problems in 101 children aged 3-6 with tuberous sclerosis complex (TSC). Some families with elevated behavior issues received a remote parent-training program called Parent-Child Interaction Therapy (PCIT) either right away or after a 6-month wait. T…

This study tested two programs to help older adults (age 55+) stop taking common sleeping pills like Ambien or Ativan. One program focused on the placebo effect—the idea that beliefs and expectations about a pill can affect sleep—while the other did not. The goal was to see if ad…

This study looked at blood samples from 24 people with Common Variable Immune Deficiency (CVID) and healthy volunteers to find better ways to diagnose the condition. Researchers used advanced technology to measure how different immune cells respond to various signals. The goal is…

This study tested a program to improve addiction care for people who use drugs in Vietnam. It involved community health workers and family members to help people seek, test, treat, and stay in treatment. Over 1,600 adults with a history of drug use took part. The goal was to see …

This study tested a patient decision aid for adults with opioid use disorder. Over 7,500 participants used the tool to help choose medication-assisted treatment. Researchers tracked drug use, treatment retention, and healthcare use for up to 24 months to see if the aid improved o…

This study looked at how a brain chemical called glutamate differs between male and female cigarette smokers. Researchers used brain scans to measure glutamate in key areas linked to withdrawal, both after a night without smoking and after the first cigarette of the day. The goal…

This study tested whether healthcare providers can help low-income parents file taxes and receive tax credits by referring them to a tax filing app. Twenty-one parents with young children took part, and researchers checked if they filed taxes and how their health changed over tim…

This study looked at whether doing kind acts for others can improve how teenagers feel. 119 teens aged 14-17 took part in a 4-week program where they either did kind acts, did kind acts plus reflected on them, or just reported their daily activities. Researchers measured their po…

This study looked at whether training classmates to interact with children with autism can improve their social connections at school. 60 children in kindergarten through 5th grade took part. Researchers measured how involved the autistic children were in their school's social ne…

This completed study looked at how inflammation might change the way younger women (ages 25-44) experience reward, such as money or smiling faces, and how that relates to depression. Researchers gave 40 healthy women a mild inflammatory substance or a placebo and measured their r…

This study looked at how stress affects eating in 453 adults with food insecurity. Participants were exposed to a stressful situation and then offered a buffet of high-calorie foods. The goal was to see if stress makes people eat more unhealthy foods. The study did not test any t…

This study looked at how to best match autism therapies to individual families. Researchers tested different sequences of parent coaching and education for 81 children aged 12-36 months with autism. The goal was to see which approach improved parent-child communication the most, …

This study looked at how inflammation impacts feelings of pleasure and motivation in older adults (ages 60-80) with anxiety. Researchers used brain scans and computer tasks to measure these effects. The goal was to better understand the link between anxiety, inflammation, and los…

This study looked at whether writing about personal experiences can affect the health of healthy women aged 60 and older. Participants wrote once a week for six weeks and completed questionnaires. Researchers also took blood samples to measure inflammation and asked about well-be…

This study explored how influenza infection changes the types of bacteria living in the nose and throat, and how the body's immune response relates to those changes. Researchers gave 17 healthy adults either a flu vaccine nasal spray or a saltwater mist, then tracked their bacter…

This study tested a new way to perform MRI and MRE scans on children that doesn't require holding their breath. Standard scans can be hard for kids, especially those with liver disease. The researchers compared the new free-breathing method to the standard one in 135 children to …

This study measured how e-hookah vaping affects the cells lining blood vessels in 33 young adults aged 21–39. Researchers compared the effects of nicotine-containing and nicotine-free vapor to see if nicotine was responsible for blood vessel damage. The goal was to understand the…

This study tested a new skin patch that measures uric acid levels in people with gout. Six participants wore the patch during a meal and for 7 days at home. The goal was to see if the patch is comfortable and can accurately track uric acid and other substances. This is an early t…

This pilot study explored whether routine genetic testing of thyroid cancer tumors can help doctors decide how much of the thyroid to remove. Only 2 people took part, and the main goal was to see if a larger study is possible. The approach aims to match surgery extent to cancer r…

This study looked at whether PTSD can damage blood vessels, which may lead to heart disease. Researchers measured how well blood vessels expand in 168 adults who had experienced trauma. The goal was to understand which PTSD symptoms are most harmful to heart health, without offer…

This study looked at whether community health workers visiting pregnant women at home in rural South Africa could improve health for both mothers and children. About 1,490 women took part, with some areas getting the home-visit program and others not. Researchers tracked things l…

This study tested two simple tools—monthly report cards and patient storyboards—to see if they could help cardiologists close gaps in preventive heart care. 46 doctors took part, and researchers tracked whether patients received recommended treatments like statins or blood pressu…

This study tested a 4-session program to help HIV+ Asian Pacific American men manage their health with support from family. Nineteen men took part to see if the program was acceptable and useful. The goal was to learn if this approach could help this community better handle their…

This study looked at whether proteins in ostomy fluid (waste from the intestine) can signal rejection after an intestinal transplant. Researchers tested fluid from 17 recent transplant recipients and compared it to biopsy results. The goal was to find a gentler, non-invasive way …

This study looked at how smoking cannabis with different amounts of THC and CBD affects people's blood, saliva, and thinking. Nineteen adults who use cannabis once a week or less took part. The goal was to learn how long these substances stay in the body and how they change feeli…

This study looked at whether taking a 10-minute cold water bath (55°F) after training helps NCAA athletes recover and perform better. 75 volleyball, football, and cross country athletes wore a WHOOP wristband to track sleep, heart rate, and other body signals. They also did jump …

This study tested a nurse-led program called HEALthy Beginnings, designed to help homeless women aged 40 and older better manage their chronic health conditions. Twenty-three women participated to see if the program was practical and well-received. The goal was to gather feedback…

This study tested a new way to look at stomach muscle activity using a magnetic capsule (a pill-sized camera). 20 people with gastroparesis or functional dyspepsia swallowed the capsule, which was guided by a magnet to record stomach contractions and measure the pylorus opening. …

This pilot study tested different outreach methods to encourage blood sugar screening in 102 overweight adults who had not been tested recently. The goal was to find undiagnosed prediabetes or type 2 diabetes earlier. Researchers compared how well each approach worked and how acc…

This study looked at inflammation in the small airways of the lungs in people with mild to moderate asthma. Researchers tested whether an inhaled steroid with small particles could reduce that inflammation better than one with large particles. 57 adults took part, using lung func…

This study tested two new tools (BOSCC and ELSA-T) for measuring changes in social communication and language in toddlers with autism. 84 minimally verbal children aged 18 months to 5 years took part in a 20-week play-based intervention called JASPER, led by a clinician or caregi…

This study tested whether a Buddhist mindfulness program could reduce the stigma felt by people living with HIV in Myanmar and Thailand. Nineteen HIV-positive participants took part, and researchers measured changes in stigma and quality of life. The goal was to understand how cu…

This study explores whether forgiving medical debt can improve people's mental health, well-being, and ability to get needed medical care. Researchers surveyed about 15,000 adults who had medical debt, some of whom had their debt forgiven by a charity. By comparing the two groups…

This study looked at whether brain wave patterns (EEG) can show early on if an antidepressant is working. Thirty-eight adults with major depression took part. The goal was to see if changes in brain activity happen before mood improves, which could help doctors choose the right t…

This study looked at how being treated unfairly because of weight affects health habits. 330 adults with a BMI of 28 or higher were randomly assigned to experience weight stigma or not. Researchers then measured their eating, physical activity, and sleep over several days to see …

This study looked at how the brains of 66 people with OCD balance between using habits and goal-directed thinking when making decisions. Researchers used brain scans (fMRI) and a mild electrical stimulation technique (tDCS) to explore the brain circuits involved. The goal was to …

This study tested two different AI scribe tools to see if they could help doctors spend less time writing notes and feel less burned out. 238 doctors at UCLA Health were randomly assigned to use one of the two AI tools or continue their usual routine for two months. The goal was …