ENDOMETRIOSIS

This study looked at over 1,100 women who had surgery for ovarian endometriomas (cysts caused by endometriosis) and then took one of four hormonal treatments to prevent recurrence. The goal was to see which treatment—birth control pills, GnRH agonists, dienogest, or dydrogesteron…

This study looked at 130 women with endometriosis who froze their eggs. It compared a drug called dienogest against standard hormone-blocking protocols to see if it could collect a similar number of mature eggs. The goal is to offer a simpler, potentially safer option for fertili…

This study tested whether freezing eggs (oocyte cryopreservation) could help preserve fertility in women with benign ovarian cysts that often come back, like endometriomas. The 82 participants had cysts that required multiple surgeries, which can damage the ovaries. Researchers m…

This study looked at 99 IVF patients with endometriosis (a condition where uterine-like tissue grows elsewhere) and a positive BCL6 test. It compared a cheap oral pill (norethindrone acetate) to an expensive injection (Depo Lupron) given before embryo transfer. The goal was to se…

This study looked at two ways to manage rectal endometriosis in women aged 35-50 who do not plan to get pregnant. One group received hormone therapy for 24 months, while the other had surgery followed by hormones. The goal was to see which approach leads to better digestive funct…

This study tested a new saliva-based test to diagnose endometriosis, a painful condition that often takes years to identify. Researchers collected saliva from over 1,100 women with confirmed or suspected endometriosis to see if the test could accurately detect the disease. The go…

This study looked at whether measuring two tiny molecules in the blood (microRNA-125b-5p and microRNA-141-3p) can accurately diagnose early-stage endometriosis. Sixty women with symptoms like pelvic pain or infertility provided blood samples and underwent standard laparoscopic su…

This study looked at whether PET scans can better detect endometriosis lesions before surgery compared to standard MRI and ultrasound. Fifteen women with symptomatic endometriosis scheduled for surgery received a PET scan, and the results were compared with what surgeons actually…

This study tested a web-based program called My Pelvic Plan for people with chronic pelvic pain, including those with endometriosis. The program teaches pain education, cognitive and behavioral skills, acupressure, physical activity, and basic pelvic floor therapy. Researchers me…

This study tested whether a TENS unit, a small device that sends mild electrical pulses through the skin, can reduce pain during endometriosis flares. Forty women with surgically confirmed endometriosis tracked their pain for three months without the device, then for three months…

This study tested two drugs, letrozole and danazol, to see which better reduces pain in women with endometriosis. Sixty women aged 18-45 with moderate to severe pelvic pain took part. Both drugs helped lower pain scores, and the study compared their effects.

This study tested whether a non-invasive brain stimulation method called tDCS can help relieve chronic pelvic pain in women with endometriosis. Thirty women who were already on hormone therapy and had daily pain scores above 4 out of 10 took part. They received multiple tDCS sess…

This study tested a new medication called OG-6219 in 354 women aged 18 to 49 with moderate to severe endometriosis-related pain. The goal was to see if three different doses could safely reduce pelvic pain compared to a placebo. The trial is complete, and results will show how we…

This study looked at whether the drug letrozole can reduce pain during ovarian stimulation (a key step in IVF) for people with endometriosis. Sixty participants were randomly assigned to receive letrozole or a placebo. The main goal was to measure changes in pain scores before an…

This study tested whether a 12-week adapted physical activity program could improve health-related quality of life in 51 women with endometriosis in Martinique. The program included aerobic, strength, and flexibility exercises. Researchers measured changes using a standard endome…

This study looked at whether following a healthy diet based on the Alternative Healthy Eating Index (AHEI) for 12 weeks could reduce pain and improve quality of life in women with endometriosis. 109 women with confirmed endometriosis and significant pain took part. Researchers me…

This study tested Korean manupuncture, a hand-based therapy, for reducing pain in women with endometriosis. 74 women were randomly assigned to receive either real or placebo sessions. The goal was to see if this gentle, non-drug approach could help manage pain that often doesn't …

This completed study compared an 8-week online yoga program to a conventional exercise routine in 52 women with endometriosis. The goal was to see if yoga could better reduce pain and improve quality of life. Participants practiced meditation, breathing, and gentle poses, while t…

This study tested two pelvic floor muscle strengthening methods—EMG-biofeedback and rebound therapy (gentle bouncing)—in 42 women with endometriosis. The goal was to see which better reduces pain, improves muscle strength, and boosts quality of life. Participants had moderate to …

This study tested a 3-month online program called PelvicSense to see if it helps reduce pain and improve sexual well-being in people with endometriosis. Twelve adults with a formal diagnosis took part entirely from home. Researchers measured pain intensity and other factors befor…

This study tested a drug called cabergoline to see if it can safely reduce chronic pain from endometriosis without using hormones. 129 women aged 15 to 40 with confirmed endometriosis and ongoing pelvic pain took part. The goal was to find a new, non-surgical way to ease pain and…

This study looked at whether yoga can reduce pelvic pain and improve quality of life for women with endometriosis. Sixty women who had pelvic pain for at least six months took part. They practiced yoga and reported their pain and well-being using standard questionnaires. The goal…

This study tested an experimental drug called HMI-115 in 142 women with moderate-to-severe endometriosis pain. Over 12 weeks, researchers compared the drug to a placebo to see if it safely reduces pain during periods and pelvic pain. The goal is to find a new treatment option for…

This study looked at different treatments for vestibulodynia, a long-term vulvar pain condition that affects about 1 in 6 women. Researchers compared a numbing cream, an oral medication, and a combination of both to see which worked best. 209 women took part, and the goal was to …

This study tested a drug called elagolix in 202 premenopausal women with moderate to severe endometriosis pain. The goal was to see if it reduces pain during periods and pelvic pain at other times. Participants took either elagolix or a placebo pill for 12 weeks, and researchers …

This study looked at whether combining yoga with pelvic floor physical therapy could help women with endometriosis feel less pain in their pelvis and during sex. 82 women took part in a 3-month program with weekly yoga and two physio sessions. The results suggest this approach ma…

This study tested a program called PEEPS for people with endometriosis-related pelvic pain. 35 participants attended weekly group sessions with a doctor, pain psychologist, physical therapist, and yoga instructor. The goal was to see if the program could reduce pain interference …

This study tested a dietary supplement made from parsley, rosemary, selenium, and other natural ingredients in 36 women with confirmed endometriosis. The goal was to see if it could reduce pain and the need for painkillers when added to their usual treatment. Results focused on p…

This study tested whether using virtual reality (VR) during a trans-vaginal ultrasound could help women with endometriosis feel less anxious and experience less pain. 155 women were randomly assigned to either use VR for relaxation during the exam or receive standard care. Resear…

This completed phase 1 study in 20 healthy men examined how SHR7280, a drug being developed for endometriosis and uterine fibroids, affects the body's processing of six other common drugs. Participants took SHR7280 alongside midazolam, warfarin, omeprazole, digoxin, and rosuvasta…

This study looked at 78 women to understand why chronic pelvic pain occurs in endometriosis. Researchers examined hormones, immune chemicals, and genes, and how nerves and muscles contribute to pain. Participants underwent tests, questionnaires, and surgery to collect samples. Th…

This study measured 14 trace elements in blood samples from 40 women with endometriosis, ovarian cancer, endometrial cancer, or healthy controls. Researchers wanted to see if levels of elements like iron, selenium, or lead differ between these groups. The goal is to find clues th…

This completed study from Guadeloupe examined whether a vaginal yeast called Candida albicans is linked to endometriosis. Researchers compared 48 women with and without the condition to see if yeast overgrowth was more common in those with endometriosis. The goal is to better und…

This study aimed to find out if severe pain during sex in women with endometriosis is linked to a condition called central sensitization, where the nervous system becomes overly sensitive to pain. Researchers measured pain-pressure thresholds and collected daily pain reports from…

This study looked at how endometriosis affects egg development and quality. Researchers analyzed fluid and cells from the ovaries of 16 women with and without endometriosis. The goal was to find clues that might explain infertility and predict which eggs could lead to a live birt…

This study tested whether using an ultrasound during surgery helps doctors decide the best way to remove endometriosis from the rectum. Ten women with deep pelvic endometriosis took part. Doctors performed an ultrasound before and after shaving off the diseased tissue to see if i…

This study tested whether artificial intelligence (AI) can automatically detect endometriosis lesions during laparoscopic surgery. Researchers used video recordings from 26 patients to train and validate an AI model. The goal was to help surgeons identify diseased tissue more acc…

This study looked at whether levels of cell free DNA (tiny DNA fragments) in blood and fluid around eggs are higher in women with endometriosis who are doing IVF. Researchers compared 114 women with and without endometriosis to see if these DNA levels relate to egg quality and pr…

This study followed over 1,400 pregnant women with endometriosis to see how the disease affects pregnancy outcomes like preterm birth and other complications. Researchers compared different types of endometriosis to better understand risks. The goal was to provide clearer informa…

This completed study looked at 2000 women with endometriosis to see if lesions and related tumors appear more often on the right or left side of the pelvis. During surgery, doctors recorded the exact location of each lesion. The goal was to better understand how endometriosis dev…

This study looked at tissue samples from 15 women with deep endometriosis to measure nerve and blood vessel growth around painful nodules. Researchers wanted to find out how far these changes spread into healthy-looking tissue, which could help surgeons know how much tissue to re…

This study looked at whether a protein called ANGPTL4 could be a better marker for endometriosis than the current CA-125 test. Researchers measured ANGPTL4 levels in the blood and pelvic fluid of 80 women—some with endometriosis and some healthy. The goal was to see if higher ANG…