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Spit test could slash endometriosis diagnosis time

NCT ID NCT05244668

First seen Mar 30, 2026 · Last updated Jun 22, 2026 · Updated 13 times

Summary

This study tested a new saliva-based test to diagnose endometriosis, a painful condition that often takes years to identify. Researchers collected saliva from over 1,100 women with confirmed or suspected endometriosis to see if the test could accurately detect the disease. The goal is to provide a simple, non-invasive tool that speeds up diagnosis and improves care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CH Bastia

    Bastia, 20600, France

  • CHU Angers

    Angers, 49933, France

  • CHU Québec

    Québec, Canada

  • CHU Rennes

    Rennes, 35000, France

  • CHU Rouen

    Bois-Guillaume, Seine-Maritime, 76230, France

  • CHU Strasbourg - Hôpital Hautepierre

    Strasbourg, Alsace, 67200, France

  • CHU Tenons

    Paris, 75020, France

  • CHU Toulouse - Hôpital Rangueil

    Toulouse, Haute Garonne, 31059, France

  • CHU de Caen

    Caen, Calvados, 14000, France

  • Cabinet de Gynécologie Médicale

    Lyon, Rhône, 69002, France

  • Centre d'imagerie Manin Crimée

    Paris, 75019, France

  • Centre médical des Pyramides

    Maurepas, Yvelines, 78310, France

  • Clinique La Sagesse

    Rennes, Ille Et Vilaine, 35000, France

  • Clinique Pasteur

    Toulouse, Haute-Garonne, 31300, France

  • Clinique Tivoli

    Bordeaux, Gironde, 33000, France

  • Groupe Hospitalier Saint Josef

    Paris, 75014, France

  • HCL

    Lyon, 69000, France

  • Hôpital BICETRE

    Le Kremlin-Bicêtre, Val De Marne, 94275, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

salivary miRNA signature test

What this could lead to

If successful, this saliva test could provide a quick, non-invasive way to diagnose endometriosis, shortening the years-long delay many women face.

What could go wrong

This is a validation study, not a treatment trial. The test may not meet the high accuracy targets, and results may not apply to all populations or settings.

Conditions

The condition(s) this trial relates to.

endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.