ENDOMETRIOSIS

This study tests a less invasive surgery called laparoscopic sclerotherapy for ovarian cysts (endometriomas) caused by endometriosis. Instead of removing the whole cyst, doctors drain it and inject a solution to shrink it, which may better protect a woman's egg supply. The study …

This study tests a new, non-invasive lab test that uses menstrual blood to diagnose endometriosis. Currently, diagnosis requires surgery, causing a 5-10 year delay for many women. The study will enroll 200 women aged 14-49 to see how accurate the test is compared to standard meth…

This study tests whether a Mediterranean diet can reduce inflammation and improve quality of life in women with endometriosis, a chronic inflammatory disease that causes pain. Researchers will enroll 104 women aged 18-45 who have been diagnosed with endometriosis and have at leas…

This study compares a new surgical method (IDLnR) to standard laparoscopic surgery for women with bowel endometriosis. The goal is to see which approach better improves bowel function and quality of life six months after surgery. About 192 premenopausal women with confirmed bowel…

This study looks at whether giving ketamine during surgery can lower pain after the procedure for people with endometriosis and chronic pelvic pain. About 126 patients will be randomly assigned to receive either standard anesthesia or standard anesthesia plus ketamine. Their pain…

This study tests a new device called Hyivy that people use at home to manage chronic pelvic pain from endometriosis. It is a small early trial with 20 adults who have endometriosis and ongoing pelvic pain. The goal is to see if the device reduces pain and improves quality of life…

This study tests whether psychological support—individual therapy, group beauty-focused sessions, or both—can improve quality of life and reduce anxiety in women with endometriosis. Forty women will be randomly assigned to one of four groups, including a no-intervention control. …

This study tests a new drug called HMI-115 for women with moderate to severe pain from endometriosis. About 540 women aged 18-49 with surgically confirmed endometriosis will receive either the drug or a placebo for 24 weeks, with a 28-week follow-up. The goal is to see if the dru…

This study aims to find out if certain environmental chemicals, called persistent organic pollutants (POPs), are linked to more severe endometriosis. Researchers will measure levels of these pollutants in blood samples from 650 women with endometriosis living in the Paris region.…

This study aims to find genetic changes in bowel tissue affected by endometriosis that might increase the risk of colorectal cancer. Researchers will compare gene activity in healthy and diseased bowel tissue from 30 women having surgery for bowel endometriosis. The goal is to im…

This study looks at the immune system of 120 women aged 18-40 with chronic pelvic pain that hasn't improved with hormone treatment. Researchers will measure specific immune markers in the blood to see if there is a unique pattern linked to the pain. The goal is to better understa…

This study looks at how the immune system and gut bacteria are linked to endometriosis, a painful condition affecting 1 in 10 women. Researchers will compare 40 women with and without endometriosis by analyzing tissue, blood, and stool samples. The goal is to find new ways to tre…

This study follows 100 women with deep endometriosis for two years to see if their lesions grow, shrink, or stay the same on ultrasound, and how their symptoms and quality of life change. Researchers want to find out if the disease always gets worse, if medical treatment affects …