Could a vaginal device ease endometriosis pain without hormones?
NCT ID NCT05643131
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 39 times
Summary
This study tests a new device called Hyivy that people with endometriosis can use at home. The device delivers gentle heat and stretches the vagina to help reduce chronic pelvic pain. Twenty adults with endometriosis and ongoing pelvic pain will use the device three times a week for 12 weeks. The goal is to see if their pain levels improve.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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McMaster University Medical Centre
Hamilton, Ontario, L8N 3Z5, Canada
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hyivy Intravaginal Device (heat and dilation therapy)
What this could lead to
If it works, this could offer a non-hormonal, at-home option to help manage endometriosis-related pelvic pain.
What could go wrong
This is a very small, early pilot study with no control group, so results may not be conclusive. The device may not reduce pain for everyone.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.