Mediterranean diet tested to ease endometriosis pain
NCT ID NCT07270393
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether following a Mediterranean diet can reduce inflammation and improve quality of life for women with endometriosis. Researchers will track pain, bloating, and fatigue in 104 women aged 18-45. The goal is to see if this anti-inflammatory diet helps manage symptoms better than usual care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Mediterranean diet
- What this could lead to
- If it works, this could point toward a simple dietary approach to ease endometriosis symptoms and improve daily life.
- What could go wrong
- This is a small, early-stage study with no control group, so results may not be conclusive. Diet changes can be hard to stick with, and benefits may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 104 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
INCLUSION CRITERIA: * Female. * Age 18-45. * Premenopausal status. * Radiological diagnosis (by transvaginal ultrasound and/or MRI) and/or surgical diagnosis of endometriosis. * Follow-up in the Gynecology Department of OSI Donostia (at least 1 visit in the last year). * Clinical score of at least 3/10 on the Numerical Scale in at least one symptom related to endometriosis). * Possibility of understanding Spanish. * Possibility of understanding the indicated dietary recommendations. * Acceptance of inclusion in clinical study, by signing informed consent. EXCLUSION CRITERIA: * Diagnosis of Eating Disorder. * Diagnosis of malabsorptive syndromes: Chron's disease, Ulcerative colitis, short bowel syndrome, gastric by-pass, irritable bowel. * Other concomitant diseases that produce CPD. * Autoimmune diseases.- * Metabolic diseases requiring follow-up of specific diets. * Diagnosed gluten intolerance. * Vegan diet. * Follow-up by a nutritionist. * Diagnosis of severe mental illness requiring treatment. * Pregnancy or current breastfeeding. * Active cancer process. * Personal history of gynecologic or digestive oncologic process. * Change of treatment or surgery during follow-up. * Surgery related to endometriosis or change of treatment in the 6 weeks prior to enrollment in the study. * Drug abuse. Opioid analgesia \< 3 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Universitario Donostia (HUD)
Donostia / San Sebastian, Gipuzkoa, 20014, Spain
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Other studies related to the condition(s) this trial covers.
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