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Which hormone best prevents endometrioma return after surgery?

NCT ID NCT07519213

First seen Apr 30, 2026 · Last updated Jun 22, 2026 · Updated 10 times

Summary

This study looked at over 1,100 women who had surgery for ovarian endometriomas (cysts caused by endometriosis) and then took one of four hormonal treatments to prevent recurrence. The goal was to see which treatment—birth control pills, GnRH agonists, dienogest, or dydrogesterone—was most effective at stopping new cysts from forming within two years. Results could help doctors choose the best post-surgery hormone therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Guangdong Women and Children Hospital

    Guangzhou, Guangdong, 511400, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hormonal treatments (combined oral contraceptives, GnRH agonists, dienogest, or dydrogesterone)

What this could lead to

If this study shows one hormonal regimen works better, it could help doctors choose the best option to prevent endometriomas from coming back after surgery.

What could go wrong

This is a retrospective study, not a controlled trial, so results may be influenced by unmeasured factors. The findings need confirmation in prospective studies.

Conditions

The condition(s) this trial relates to.

endometriosis ovarian endometriosis Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.