Endometriosis sex pain: is your nervous system to blame?
NCT ID NCT03216330
First seen Apr 18, 2026 · Last updated Jun 21, 2026 · Updated 8 times
Summary
This study aimed to find out if severe pain during sex in women with endometriosis is linked to a condition called central sensitization, where the nervous system becomes overly sensitive to pain. Researchers measured pain-pressure thresholds and collected daily pain reports from 56 women over six weeks. No treatment was given; the goal was simply to understand the connection better.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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BC Children's and Women's Hospital
Vancouver, British Columbia, V6H2N9, Canada
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors better understand why some women with endometriosis have severe pain during sex, potentially leading to better pain management approaches.
What could go wrong
This is an observational study with no treatment, so it cannot prove cause and effect. The small size (56 participants) and focus on one clinic limit how widely the results can be applied.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.