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Endometriosis pain study seeks to uncover why sex hurts

NCT ID NCT03216330

Knowledge-focused Sponsor: BC Women's Hospital & Health Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 56 women with endometriosis to see if severe pain during sex is linked to a condition called central sensitization, where the nervous system becomes overly sensitive to pain. Researchers used pain-pressure tests and daily surveys over 6 weeks to measure pain levels. The goal was to better understand the causes of deep pelvic pain during intercourse, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

56 people

The number who actually took part.

Started

Jul 2017

Finished

Apr 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Tertiary care centre (BC Women's Health Centre for Pelvic Pain and Endometriosis) for case participants. Community sample for control participants.

Ages

18 to 49 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Case: * Consented to participate in the Data Registry (H16-00264) prior to their physician appointment at the BC Women's Health Centre. * New or re-referred to the BC Women's Health Centre for Pelvic Pain and Endometriosis. * Endometriosis (previously surgically diagnosed, or current endometrioma, or current nodule) * Willing and committed to indicating pain scores and menstrual data on a REDCap survey every day for 6 weeks after the test date. * At least 18 years old * Control: * Reproductive aged female with no suspected or diagnosed endometriosis. * Have not experienced any sexual pain scores over 4/10 on a 11-point numeric rating scale, as determined on an online questionnaire prior to test day. * At least 18 years old Exclusion Criteria: \- Case and Control: * Fibromyalgia. * Severe and enduring psychological illness(es) affecting cognition (e.g., bipolar disorder, schizophrenia etc.). * Currently pregnant or breastfeeding. * Have a peripheral or central neurological disorder. * Have diabetes mellitus or neuropathic pain. * Do not speak English. * Have had previous physical trauma (ex. Surgery) to the test site(s) (deltoid muscle in the shoulder, and first dorsal interosseous muscle).

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Conditions

The condition(s) this trial relates to.

endometriosis psychologic dyspareunia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Central sensitisation Dyspareunia Endometriosis

Contacts and locations

Locations

  • BC Children's and Women's Hospital

    Vancouver, British Columbia, V6H2N9, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.