University Of Miami

This study compares two methods of offering HIV, hepatitis C, and addiction medications to 100 people who inject drugs. Participants are already part of syringe service programs in Miami and Tampa. The goal is to see which method helps more people achieve HIV viral suppression an…

This study tests whether giving a higher dose of radiation to the exact spot where prostate cancer has returned (seen on an MRI) can better lower PSA levels in men who have already had their prostate removed. 37 men with a rising PSA after surgery are participating. The goal is t…

This study tests whether adding daratumumab to a standard three-drug regimen (carfilzomib, lenalidomide, dexamethasone) can better control multiple myeloma in newly diagnosed patients. About 310 participants will receive either the three-drug or four-drug combination. The main go…

This study tested whether a shorter, more intense course of radiation (5 sessions) works as well as the standard longer course (26 sessions) for prostate cancer. It involved 161 men with early-stage prostate cancer. The main goal was to see if the shorter treatment controls the c…

This study tests whether giving an extra-high dose of radiation to the most aggressive parts of prostate tumors, guided by MRI scans, can improve cancer control while protecting nearby organs. About 164 men with prostate cancer will receive either this boost plus standard radiati…

This study tested a one-time intravenous infusion of donor stem cells in people who had a recent ischemic stroke (within 9 days). The goal was to see if the cells could help the brain heal and improve recovery. Participants were adults aged 18 to 80 with a moderate stroke in a sp…

This study looks at whether giving a single high dose of vitamin D before hip or knee replacement surgery can lower the chance of complications, like infection, in patients who have low vitamin D levels. About 200 adults with low vitamin D will take part. The goal is to see if co…

This study tests whether liraglutide, a medication that reduces fat and promotes weight loss, can shrink the fat deposits around the heart and help stabilize heart rhythm in people with atrial fibrillation (AFib). About 60 adults with AFib and a BMI of 27 or higher will receive l…

This study looks at whether adding an inhaled corticosteroid (ICS) to standard COPD treatment for 4 weeks can improve how well the blood vessels in the lungs work. It involves 30 adults aged 40-80 with COPD who already use a LAMA/LABA inhaler. The main goal is to see if the ICS h…

This study screens 500 adults in South Florida for H. pylori, a stomach infection that can lead to chronic gastritis, ulcers, and even stomach cancer. Those who test positive receive free treatment right away. The goal is to catch and treat the infection early to prevent serious …

This study looks at the best ways to prevent anxiety and depression in older Latino adults (age 60+) who have mild symptoms but not a full disorder. About 240 participants will join either a health promotion program or a healthy lifestyles education class. Researchers will track …

This study screens people in South Florida for H. pylori, a stomach infection that can lead to chronic inflammation, ulcers, and even stomach cancer. Those who test positive receive treatment, and the study compares at-home retesting versus standard retesting to confirm the infec…

This study compares two procedures—prostate artery embolization (PAE) and holmium laser enucleation (HoLEP)—to see which better improves symptoms of an enlarged prostate in men with prostates larger than 80 grams. About 45 men aged 50 and older with moderate to severe symptoms wi…

This study tests whether injections of platelet-rich plasma (PRP) into the vulva and vagina can improve symptoms of genitourinary syndrome of menopause (GSM) in breast cancer survivors. GSM causes dryness, burning, and pain, especially after cancer treatments. The trial enrolled …

This study tests whether cyproheptadine, a medicine that boosts appetite, can improve eating habits in children aged 2 to 6 with pediatric feeding disorders. Researchers will track changes in eating behavior, food variety, and growth over time. The goal is to find a safe, simple …

This study tests a program that combines mindfulness and music therapy, delivered through an app or website, for people undergoing a stem cell transplant. The goal is to see if it helps improve quality of life and reduce symptoms like pain. About 60 adults with certain blood canc…

This study tests whether a mobile app called Horizons can help improve quality of life for adults who have chronic graft-versus-host disease after a stem cell transplant. About 20 participants will use the app and complete surveys. The goal is to see if the app is easy to use and…

This study is testing a program called U-PEACE for high school students who are struggling with emotions like anxiety and depression, as well as schoolwork. About 72 teens aged 13 to 18 will take part to see if the program helps them feel better and do better in school. Researche…

This study looks at whether improving diet quality can help manage chronic pain in people with spinal cord injury. Thirty adults with SCI and ongoing pain will follow a nutrition program for 4 months. Researchers will measure changes in pain intensity and nerve-related pain befor…

This study looks at whether a group-based program called Horizons can help adults with chronic graft-versus-host disease (cGVHD) improve their quality of life and coping skills. About 20 people who had a stem cell transplant and now have moderate to severe cGVHD will take part. T…

This study looks at how hidradenitis suppurativa (HS) affects physical activity and tests a custom exercise program designed to improve strength and daily function. Researchers will measure changes in leg and hand strength, walking ability, and quality of life in 86 adults with H…

This study tests a new online program called ORCHID, designed to help aging women with HIV feel better emotionally and stay in care. The program teaches skills to build positive feelings and cope with stress. Researchers will enroll 30 women from a Miami HIV clinic to see if the …

This study tested a 1726nm laser (AviClear) on 8 adults with mild to moderate hidradenitis suppurativa (HS), a painful skin condition. The goal was to see if the laser safely reduces painful bumps and lesions. Researchers measured improvement using a standard score (HiSCR50) and …

This study looks at blood samples from 400 people with and without HIV who either use or do not use opioids. The goal is to understand how opioids affect the body's immune response to the flu vaccine. Researchers will measure antibody levels and immune cell activity to see if opi…

This study looks at the bacteria and fungi living in the urinary tract of people with calcium kidney stones or kidney cancer, compared to healthy volunteers. Researchers will collect urine, stone fragments, and tissue samples to map the microbial community. The goal is to better …

This study aims to learn more about ALS and similar diseases like frontotemporal dementia and hereditary spastic paraplegia. Researchers will look at how a person's genetic makeup relates to their symptoms and will search for biological markers (biomarkers) in blood and spinal fl…

This study looks at whether a blood test that tracks tumor DNA can help doctors switch treatments earlier in people with stage IV breast cancer. The goal is to see if acting on this early signal can keep the cancer under control longer than waiting for scans to show growth. About…

This study looks at how feeling fear in virtual reality (VR) changes a person's ability to empathize with others. Researchers will measure empathy and heart rate in 110 young adults before and after a fear-inducing VR experience. The goal is to understand the link between shared …

This study tracks biological markers (biomarkers) in people with ALS and related disorders, as well as healthy volunteers, to better understand how these diseases progress. The goal is to help design better clinical trials for future treatments. No experimental treatments are giv…

This study collects information from 1,200 pregnant people with a certain type of twin pregnancy (monochorionic) to better understand complications like twin-to-twin transfusion syndrome. Researchers will track pregnancy and baby outcomes, such as preterm birth and infant death. …

This study looks at people with early ALS to find the very first signs of the disease in parts of the body not yet affected. Researchers will track 100 participants over time to see how and when symptoms spread. The goal is to better understand ALS, not to test a treatment.

This study looks at whether a friendly robot can help children with asthma learn how to manage their condition. About 120 children and their parents will try out the robot's lessons and activities. Researchers want to see if families find the robot easy to use and helpful.