Oxygen study aims to uncover hidden heart risks in breathing disorders

NCT ID NCT05606406

Terminated Knowledge-focused Sponsor: University of Miami Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 2 times

Summary

This study will test how changes in oxygen levels affect the heart's electrical signals in 70 people, some with oxygen dependence and some healthy. Participants will receive increasing amounts of oxygen at night while their heart activity is monitored. The goal is to better understand the link between low oxygen and heart rhythm changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nocturnal oxygen
What this could lead to: If successful, this could help doctors better understand how low oxygen affects the heart, potentially improving care for people with COPD or other breathing problems.
What could go wrong: This is a small, early-stage study (70 people) that only measures heart signals, not health outcomes. It may not lead to any direct treatment or change in care.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset Hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPOXIA PULMONARY DISEASE, CHRONIC OBSTRUCTIVE

Contacts and locations

Locations

University of Miami

Miami, Florida, 33136, United States

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