Can a blood injection ease menopause symptoms in breast cancer survivors?

NCT ID NCT05812924

Ongoing Symptom relief Sponsor: University of Miami Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether injecting platelet-rich plasma (PRP) into the vulva and vagina can improve symptoms of genitourinary syndrome of menopause (GSM) in breast cancer survivors. GSM causes dryness, burning, and pain, often worsened by cancer treatments. The study enrolls 18 women and measures symptom changes using questionnaires and a vaginal health index.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: platelet-rich plasma (PRP) injections
What this could lead to: If it works, this could offer a new, non-hormonal option to relieve vaginal dryness and discomfort in breast cancer survivors.
What could go wrong: This is a small, early-phase trial with only 18 participants, so results may not apply widely. PRP injections may cause pain or infection, and the benefit is not yet proven.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm postmenopausal atrophic vaginitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER GENITOURINARY SYNDROME OF MENOPAUSE

Contacts and locations

Locations

University of Miami

Miami, Florida, 33136, United States

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