University Of Miami

This study looks at whether playing active video games can help children, teenagers, and young adults (ages 5-21) with obesity and type 2 diabetes lose weight and improve their blood sugar levels. Participants will play active video games at home, and researchers will track chang…

This study tests injecting the chemotherapy drug cisplatin directly into throat cancer tumors that have come back after radiation. About 20 adults will receive the injection before planned surgery. The goal is to see if this approach can shrink or eliminate the tumor, while also …

This pilot study tests whether injecting doxycycline, an antibiotic that can also scar tissue, helps treat fluid collections (seromas) that form after orthopedic surgery. Ten adults with a seroma will receive the injection and be followed to see if the fluid comes back or turns i…

This study tests a special type of radiation therapy guided by MRI to treat spinal tumors that are pressing on the spinal cord. The goal is to see if this treatment can control the tumor and avoid the need for surgery. The study will include 24 adults with solid tumors that have …

This study looks at whether testosterone replacement therapy is safe for men who have both low-risk prostate cancer and low testosterone (hypogonadism). Researchers will monitor 35 men over 12 months to see if the treatment causes their cancer to worsen or requires more aggressiv…

This study looks at whether using stitches coated with an antibiotic (triclosan) is as good as or better than standard stitches for people with infected hip or knee replacements who are having a surgery called DAIR (debridement, antibiotics, and implant retention). About 142 adul…

This study looks at whether offering a simple blood test (called Shield) can encourage more people who are overdue for colon cancer screening to get checked. About 500 adults aged 45-85 will be randomly assigned to either receive a standard reminder or also have the option to giv…

This study looks at whether 12 weeks of Transcendental Meditation can lower stress and blood pressure in postmenopausal women who are at risk for hypertension. Sixty women aged 50-80 with mildly high blood pressure and stress will be randomly assigned to either a meditation progr…

This study looks at whether giving women a single dose of antibiotics during a routine clinic procedure for stress urinary incontinence (called urethral bulking) can lower their chance of getting a urinary tract infection afterward. About 150 women will take part, and half will r…

This study tests a program called PrEP & Soccer, run through CVS pharmacies, to help men learn about and get PrEP (a daily pill that prevents HIV). The program uses soccer-themed materials to reach men, especially Latino men who have sex with men. Researchers will see if this app…

This study tests an online program that combines mindfulness and music therapy to help people undergoing stem cell transplants feel better and have fewer symptoms. About 165 adults with blood cancers like leukemia or lymphoma will take part. The goal is to see if this approach im…

This study is testing a new web-based program designed to help people with pancreatic cancer reduce stress and manage symptoms. Researchers will enroll 60 adults who speak English or Spanish and have pancreatic cancer. The program involves biweekly calls and surveys to see if it'…

This study tests a stepped-care version of Parent-Child Interaction Therapy (PCIT) for children aged 2 to 7 who have a mild to moderate traumatic brain injury and behavior problems. About 20 parent-child pairs will learn skills to improve behavior and reduce parent stress. The go…

This study tests whether cetirizine (Zyrtec) causes less sleepiness than diphenhydramine (Benadryl) when given before MS infusions. About 60 adults with multiple sclerosis will take one of the two medicines before their anti-CD20 therapy. The goal is to find which pre-medication …

This study looks at whether using a device called the Alexis wound retractor during hip replacement surgery helps wounds heal better and reduces infections. About 202 adults with hip arthritis having their first hip replacement will take part. Researchers will compare healing tim…

This study tests whether a remote group stress management program (R-CBSM) can help women aged 50+ who have finished breast cancer treatment but still feel stressed. Participants learn relaxation and coping skills via video calls. The goal is to see if this reduces distress and s…

This study looks at whether practicing mindfulness breathing exercises can improve physical health and quality of life for people with spinal cord injury. Ten adults aged 18-70 with injuries between C5 and T10 will take part. Researchers will measure heart rate, blood pressure, a…

This study will test if a special laser (1726nm) can safely shrink or remove small bumps that appear on the face in people with frontal fibrosing alopecia, a type of hair loss. Ten adults with these facial bumps will receive the laser treatment. Doctors will measure changes in bu…

This study compares two methods to control pain after total knee replacement: a new long-acting painkiller (Zynrelef) injected into the knee during surgery versus a standard nerve block. Researchers will measure how much opioid pain medication patients need in the first 72 hours …

This study tests a brief online program called Project Independence for caregivers of autistic youth ages 10 to 14. The program gives caregivers practical tools to help their child become more independent in daily tasks like getting dressed or doing chores. About 70 caregivers wi…

This study looks at how a short, home-based high-intensity workout affects steroid hormones in men with low-grade prostate cancer who are on active surveillance. Researchers will collect saliva samples before and after the exercise to measure hormone changes. The goal is to under…

This study looks at how changes in oxygen levels affect the heart's electrical signals in people with and without oxygen dependence. Researchers will measure heart rate variability and other ECG readings in 70 participants. The goal is to better understand the link between low ox…

This study tests whether a personalized AI coach that adapts to your real-time performance can help you cycle harder during a 20-minute time trial. Researchers will compare the AI coach to simple motivational phrases and to no coaching at all. The study involves 120 recreationall…

This study tests whether messages created by artificial intelligence can change how cancer survivors think about alcohol and cancer risk. About 850 adults who have had certain cancers and currently drink alcohol will receive either a gain-framed or loss-framed message. Researcher…