University Of Miami

This small, early-stage study is testing if a drug called Emapalumab can help control a severe, fast-worsening lung disease linked to a specific immune system antibody (anti-MDA5). The drug, already used for another serious immune condition, will be given to 5 adults to see if it…

This small pilot study is testing whether injecting the antibiotic doxycycline can help treat persistent fluid collections (seromas) that sometimes form after knee or hip replacement surgery. The goal is to see if this injection can shrink these fluid pockets and reduce the need …

This study is testing whether a highly precise form of radiation therapy, guided by real-time MRI scans, can effectively control tumors pressing on the spinal cord. The goal is to see if this treatment can help patients with metastatic cancer avoid major decompressive spine surge…

This study tests whether injecting chemotherapy directly into recurrent throat cancer tumors can shrink them before surgery. Researchers will enroll 20 adults whose cancer returned after radiation treatment. Participants will receive three weekly injections followed by standard s…

This study aims to find out if testosterone replacement therapy is safe for men who have both low-risk prostate cancer and low testosterone levels. It will follow 35 men who are on active surveillance for their cancer to see if the testosterone treatment causes their cancer to wo…

This study will compare two approaches to hip replacement surgery to see if using a special wound retractor device leads to better healing and fewer infections. Researchers will enroll 202 people with hip osteoarthritis who are getting their first hip replacement through a specif…

This study is testing if using stitches coated with an antibiotic (triclosan) can help prevent infections from coming back after surgery to clean infected hip or knee replacements. It will compare these special stitches to the standard stitches currently used. The goal is to see …

This study aims to see if offering a blood test option alongside standard reminders helps more people complete recommended colon cancer screening. Researchers will compare two groups: one gets standard mail/email reminders, and the other gets those same reminders plus the option …

This study will test if learning Transcendental Meditation helps prevent high blood pressure in postmenopausal women who are at risk. Researchers will compare meditation to standard health education classes over 12 weeks. The goal is to see if this non-drug approach can improve s…

This study is testing a new program called 'PrEP & Soccer' at CVS pharmacies to see if it can help more men learn about and get appointments for PrEP, a daily pill that prevents HIV. The program will be offered to 800 Latino men in Florida who are at higher risk for HIV. Research…

This study is testing whether a friendly robot can be a good teacher for children with asthma. Researchers want to see if kids and their parents find the robot easy to use and helpful for learning how to manage asthma, especially using an inhaler correctly. The main goal is to ch…

This study aims to see if practicing mindfulness breathing exercises can improve the physical health and quality of life of people living with spinal cord injuries. Researchers will measure changes in heart rate, blood pressure, metabolism, and life satisfaction in 10 participant…

This study is testing a new online program designed to help people with pancreatic cancer manage stress and difficult symptoms like pain, fatigue, and poor sleep. The goal is to see if the program is practical for patients to use and if it improves their quality of life. Research…

This study aims to find out which common allergy medicine works better as a pre-treatment before MS infusion therapy. Researchers will compare cetirizine (like Zyrtec) with diphenhydramine (like Benadryl) in 60 MS patients receiving specific infusion treatments. The main goal is …

This study is testing whether a specific laser treatment can safely reduce the size and number of facial papules (small bumps) in people with frontal fibrosing alopecia (FFA), a condition that causes hair loss and skin changes. Researchers will enroll 10 adults with FFA and treat…

This study is testing if adding a common moisturizing ingredient (sodium hyaluronate) to personalized serum eye drops makes them work better for people with moderate-to-severe dry eye disease. Each of the 20 participants will use the new formula in one eye and the standard formul…

This study is testing whether listening to binaural beats (special audio tones) or music of your choice can help reduce pain and anxiety right after knee or hip replacement surgery. Researchers will compare these audio methods in 50 adults recovering from surgery. They will measu…

This study is testing whether an online program combining mindfulness and music therapy can help patients feel better during and after a stem cell transplant. It aims to improve quality of life, reduce symptoms like pain and fatigue, and lower stress for 165 adults with blood can…

This study is testing whether personalized AI coaching can help people cycle harder and perform better during indoor workouts. Researchers will compare three approaches: adaptive AI coaching that gives real-time feedback, pre-set motivational messages, and exercise with no extra …

This study compares two different approaches to managing pain after knee replacement surgery. Researchers want to see whether a long-acting numbing medication injected around the knee joint works better than a nerve block in the thigh at reducing the need for opioid painkillers. …

This study aims to test different AI-generated messages about alcohol use and cancer risk. Researchers want to see if certain message styles can change cancer survivors' perceptions about alcohol harm and their intentions to reduce drinking. The study involves 850 adult cancer su…

This small pilot study aims to find out how much sterile fluid is needed to visibly clean out contamination during surgery for an infected knee replacement. Researchers will use a safe blue dye during surgery to simulate germs and measure how much washing it takes for the dye to …

This study aims to understand how eating affects metabolism, heart health, and feelings of hunger in men with high spinal cord injuries. Researchers will compare 56 inactive men—some with spinal injuries and some without—by measuring their body's energy use after meals and their …

This study aims to understand how the body's demand for oxygen affects the electrical activity of the heart. Researchers will compare heart rhythm patterns in healthy people and in people with chronic lung conditions who have low oxygen levels. The goal is to gather knowledge, no…

This study aims to understand how common asthma medications affect air and blood flow in the lungs. Researchers will use special imaging scans on 40 adults with asthma before and after they take their regular inhaler medication. The goal is to gather detailed information about ho…

This research aims to understand how watching other people experience fear in virtual reality affects a person's ability to empathize. It will measure changes in self-reported feelings and heart rate in 110 young adults. The study is observational and does not test a treatment.