University Of Miami

This study looks at whether playing active video games can help children and young adults (ages 5-21) with obesity and type 2 diabetes lose weight and lower their blood sugar levels. Participants will play active video games at home, and researchers will track changes in weight a…

This study tests whether a specially designed anti-inflammatory diet can reduce symptoms and gut inflammation in people with mild-to-moderate Crohn's disease. For 8 weeks, 122 participants will receive fully catered meals and weekly coaching from a dietitian. The goal is to see i…

This study will test a doula support program for 15 pregnant women with HIV in South Florida. The doula will provide education, adherence support, and lactation counseling from pregnancy through 12 weeks after birth. The goal is to see if this program is feasible and acceptable, …

This small study will test a drug called emapalumab in 5 adults with a rare, rapidly worsening lung disease linked to dermatomyositis. The drug is already used for a similar immune overreaction condition. Researchers will check if it improves oxygen needs, lung function, and CT s…

This small study tests whether injecting doxycycline into fluid pockets (seromas) that form after joint replacement surgery can help them go away and prevent them from coming back. Ten adults with a seroma after an orthopedic procedure will receive the injection and be followed w…

This study tests a precise, MRI-guided radiation treatment for people with cancer that has spread to the spine and is pressing on the spinal cord. The goal is to shrink the tumor enough to avoid surgery. About 24 adults with solid tumors like breast, prostate, or lung cancer will…

This study tests whether antibiotic-coated braided sutures work as well as standard monofilament sutures in patients with infected hip or knee replacements. Surgeons currently use weaker monofilament sutures in infected cases to reduce bacterial growth. If the coated braided sutu…

This study looks at whether testosterone replacement therapy (TRT) is safe for men with low-risk prostate cancer who also have low testosterone. Researchers will monitor 35 men for 12 months to see if the cancer gets worse or if they need stronger treatment. The goal is to help m…

This study looks at whether offering a blood test (Guardant Shield) can increase colon cancer screening in people who are overdue. About 500 adults aged 45-85 will either get a standard reminder to screen or also have the option to give a blood sample. The goal is to see if the b…

This study will test whether a 12-week Transcendental Meditation (TM) program can improve stress, mood, and blood pressure in post-menopausal women at risk for hypertension. Sixty women aged 50-80 with mildly elevated blood pressure and stress will be randomly assigned to TM or a…

This study looks at whether giving women a single dose of antibiotics right before a clinic-based urethral bulking procedure (for stress incontinence) can lower their chance of getting a urinary tract infection afterward. About 150 women will be split into two groups: one gets th…

This study tests a program called PrEP & Soccer, run through CVS pharmacies, to help men learn about and start PrEP—a daily pill that prevents HIV. About 800 men aged 18-54 who are at risk for HIV will take part. Some pharmacies will offer personalized PrEP navigation and a socce…

This study is testing a new web-based program designed to help people with pancreatic cancer manage stress and symptoms. Sixty participants will complete weekly one-hour online sessions for ten weeks, learning relaxation, coping, and communication skills. The goal is to see if th…

This study compares two pain relief methods after total knee replacement: a long-acting pain shot (Zynrelef) given directly into the knee during surgery versus a standard nerve block. The goal is to see which method better reduces the need for opioid painkillers in the first 72 h…

This study tests whether adding Eroxon gel to the standard pill tadalafil can improve erections in men aged 18 to 40 with type 2 diabetes. Thirty men who already take tadalafil will use the gel before sex and report changes in erectile function. The goal is to see if the combinat…

This study tests whether a virtual reality (VR) program that combines special sounds, lights, and real-time body feedback can lower stress and improve heart health markers in 40 adults visiting a cardiology clinic. Participants will be randomly assigned to VR, a non-VR relaxation…

This study tests a stepped-care version of Parent-Child Interaction Therapy (PCIT) for children aged 2 to 7 who have a mild to moderate traumatic brain injury and behavior problems. The program teaches parents positive parenting skills through online modules and weekly therapist …

This study tests if a special laser (1726nm) can safely shrink small bumps that appear on the face in people with frontal fibrosing alopecia (FFA). Ten adults with FFA and facial papules will receive the laser treatment. Doctors will measure changes in bump size and number using …

This study tests if adding sodium hyaluronate (a common moisturizer in artificial tears) to autologous serum eye drops provides better relief for moderate-to-severe dry eye disease. About 20 adults with dry eye from conditions like Sjögren's syndrome will use the new mix in one e…

This study tests an online music therapy program that combines mindfulness and music to help people recovering from stem cell transplants for blood cancers. Researchers want to see if it can improve quality of life, reduce pain, fatigue, anxiety, and depression, and possibly spee…

This study tests whether a 10-week remote stress management program (R-CBSM) can reduce distress and slow aging in 192 breast cancer survivors aged 50+. Participants attend group video sessions on relaxation and coping skills. Researchers will measure changes in stress, immune ce…

This study looks at whether different doses of steroid injections work equally well for treating sciatica (nerve pain in the lower back and leg). About 150 adults with MRI-confirmed lumbar radiculopathy who have not had back surgery will receive one of several doses of either tri…

This study tests whether cetirizine (Zyrtec) causes less sleepiness than diphenhydramine (Benadryl) when used as a pre-medication before anti-CD20 infusions for multiple sclerosis. Sixty participants will receive either drug 30-60 minutes before their infusion, and researchers wi…

This study tests whether an AI coach that gives personalized encouragement during indoor cycling can help people ride harder. 120 recreationally active adults aged 18-40 will do a 20-minute time trial on a stationary bike. Some will get AI-powered affirmations, some will get fixe…

This study looks at whether using a device called the Alexis wound retractor during hip replacement surgery helps wounds heal faster and reduces infections. About 202 adults with hip arthritis having a first-time hip replacement will take part. Researchers will compare healing, s…

This study looks at how a short, home-based high-intensity workout affects steroid hormones in men with low-grade prostate cancer who are on active surveillance. About 49 men will do one supervised bodyweight HIIT session and provide saliva samples. The goal is to see if the exer…

This study will test how changes in oxygen levels affect the heart's electrical signals in 70 people, some with oxygen dependence and some healthy. Participants will receive increasing amounts of oxygen at night while their heart activity is monitored. The goal is to better under…