One pill before a bladder procedure might slash infection risk

NCT ID NCT07501065

Not yet recruiting Prevention Sponsor: University of Miami Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether giving women a single dose of antibiotics right before a clinic-based urethral bulking procedure (for stress incontinence) can lower their chance of getting a urinary tract infection afterward. About 150 women will be split into two groups: one gets the antibiotic, the other does not. Researchers will track infections for six weeks after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bactrim (sulfamethoxazole/trimethoprim) or Macrobid (nitrofurantoin)
What this could lead to: If it works, this could provide a simple way to reduce urinary tract infections after a common incontinence procedure.
What could go wrong: This is a small, early-phase study with only 150 participants, so results may not apply to everyone. Antibiotics can also cause side effects or contribute to antibiotic resistance.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

female stress incontinence Urinary Incontinence Urinary Incontinence, Stress urinary tract infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STRESS URINARY INCONTINENCE URINARY INCONTINENCE URINARY TRACT INFECTIONS

Contacts and locations

Locations

Desai Sethi Urology Institute

Miami, Florida, 33136, United States
University of Miami Hospitals and Clinics

Miami, Florida, 33136, United States

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