Ohio State University Comprehensive Cancer Center

This study is testing a new way to give radiation to women with early-stage breast cancer. During their standard lumpectomy and reconstruction surgery, doctors give a single, targeted dose of radiation directly to the area where the tumor was. The goal is to see if this approach …

This small pilot study is testing whether robot-assisted surgery can safely perform nipple-sparing mastectomies for early-stage breast cancer or risk reduction. Researchers want to see if using robotic tools through small incisions can remove breast tissue completely while preser…

This small pilot study is testing whether a ketogenic diet (very low in carbs, high in fat) can help improve treatment outcomes for people with brain metastases when combined with standard radiation therapy. It compares the ketogenic diet to a standard cancer diet over 16 weeks i…

This study is testing whether adding a drug called venetoclax to an existing treatment (ibrutinib) can help patients with chronic lymphocytic leukemia (CLL) whose cancer has become resistant. The goal is to eliminate the genetic changes that cause resistance and better control th…

This early-stage study is testing whether adding a drug called papaverine to a precise form of radiation therapy makes the treatment more effective for patients with non-small cell lung cancer or lung tumors that have spread. The main goal is to find the safest dose of papaverine…

This study is testing whether combining two drugs, ibrutinib and nivolumab, can help control classical Hodgkin's lymphoma that has returned or hasn't responded to previous treatments. The trial involves 18 adults who have already had at least one prior therapy. Researchers want t…

This study is testing small, wearable sensors that stick to the skin to see if they can detect early signs of arm swelling (lymphedema) in cancer survivors. Researchers want to see if these sensors, which measure tiny changes in tissue, can tell the difference between a healthy a…

This study tested whether sending educational materials to parents and healthcare providers could increase the number of girls getting the HPV vaccine in 12 Appalachian counties in Ohio. Researchers compared two groups: one received information about the HPV vaccine, and the othe…

This early-stage study is testing different types of black raspberry candy to see which version best delivers the berry's healthy compounds to the body. Healthy volunteers try candies that release the berry's ingredients at different speeds to find the most effective formula. The…

This study is testing a program designed to help women in rural communities quit smoking. The goal is to prevent cervical cancer, which is linked to smoking. The program trains local healthcare providers and offers women counseling sessions to support their quit attempts.

This study is testing whether a 12-week program of virtual exercise classes and group counseling can change gut bacteria and reduce body-wide inflammation in people at high risk for lung cancer. Researchers want to see if this approach is practical and if it improves health marke…

This early-stage trial is testing a new vaccine designed to prevent infections from Epstein-Barr virus (EBV) and the cancers it can cause. The study will enroll healthy volunteers and patients awaiting organ transplants, who are at higher risk for EBV-related cancers due to their…

This study is testing if sending text messages about the health risks of smoking and vaping can help LGBTQ+ young adults quit or change their tobacco use. Researchers are sending different types of risk messages to 300 participants over 6 weeks to see which approach works best. T…

This study tests whether early neuropsychological evaluation and support helps patients with brain metastases maintain their quality of life and thinking abilities after radiation therapy. Researchers are comparing two groups: one receiving specialized neuropsychological care alo…

This study is testing a website called YES, designed to help young women who have finished breast cancer treatment. The goal is to see if using this website to track and manage symptoms improves their quality of life better than standard follow-up care. About 400 young survivors …

This study aims to compare how accurately three different food questionnaires estimate people's intake of nutrients from fruits and vegetables. Researchers will have 100 healthy adults complete the questionnaires and compare the results to their actual diet records and blood meas…

This study aims to understand how e-cigarette use affects breathing in overweight young adults. Researchers will measure lung function before and after vaping sessions in 56 participants aged 21-25. The study compares vaping habits and breathing changes between overweight and nor…

This study aims to find early signs of heart damage in cancer patients receiving radiation therapy to the chest. Researchers will use special heart scans and blood tests on 28 participants before, during, and after their radiation treatment. The goal is to learn how to identify p…

This research aims to identify genetic factors that increase the risk of papillary thyroid cancer in families. Participants with thyroid cancer and multiple affected relatives provide family history information and DNA samples. The study analyzes genetic patterns to understand he…

This study aims to understand the short-term health effects of using e-cigarettes. Researchers are comparing 75 e-cigarette users with 75 non-users, measuring their lung function and inflammation before and after a vaping session. The results will help create better health polici…

This study is collecting and analyzing information about patients who had robotic surgery to remove their prostate due to cancer. Researchers are looking at how patients do after surgery, including survival rates and whether cancer returns. The goal is to understand which patient…

This study aims to learn if simple blood tests can predict how well patients with lung or kidney cancer will respond to immunotherapy drugs. Researchers will collect blood and stool samples from 100 patients receiving standard immunotherapy treatment to look for patterns. The goa…

This study is testing a new nanochip technology that analyzes blood samples to monitor how well treatment is working and to try to detect if cancer returns earlier in patients with diffuse large B-cell lymphoma. Researchers will collect blood from 73 patients at diagnosis, during…

This small study aims to understand how hormone therapy for prostate cancer affects heart function and muscle health. Researchers will use special heart scans and muscle tests on 23 patients before they start treatment and again 4-7 months later. The goal is to gather information…

This study is testing whether a new, more convenient online genetic counseling approach works as well as traditional in-person counseling for women at higher risk for breast cancer. Researchers are comparing two methods: one uses educational videos and online tools through a pati…

This study is testing whether a short educational video can help patients with advanced cancer better understand tumor genomic testing. It involves 243 adults with metastatic breast or lung cancer who are already scheduled for this type of testing. Researchers will measure if wat…

This study is testing a small change to a common lung cancer biopsy procedure to see if it gets better samples. Doctors are comparing tissue samples taken with and without a gentle suction during the biopsy. The goal is to see if suction helps collect more usable tissue with less…