Ohio State University Comprehensive Cancer Center

This study tested whether adding the drug romidepsin to a stem cell transplant could better control several aggressive types of T-cell blood cancers. Researchers gave romidepsin before and after the transplant to 23 patients to find the safest dose and see if it helped. The main …

This study tested a two-drug combination (fulvestrant and palbociclib) to control breast cancer in patients aged 70 and older who could not undergo surgery due to frailty or who refused it. The goal was to see if this non-surgical approach could keep the cancer from growing for a…

This study tested whether combining two drugs could help control chronic lymphocytic leukemia and related blood cancers. It included 41 adults whose cancer had returned after previous treatment or who hadn't yet received treatment. Researchers gave patients an antibody drug that …

This small, completed study tested whether a short, highly targeted course of radiation given before surgery was a safe and practical option for older women with early-stage, hormone-sensitive breast cancer. The goal was to see if this approach could shrink the tumor and potentia…

This study tested a combination of two drugs, ruxolitinib and CPX-351, for patients with advanced forms of certain blood cancers that had worsened. The main goals were to find the safest dose of the combination and to see how well it worked to control the cancer. The trial involv…

This study tested whether a short video could help people who carry a BRCA gene mutation encourage their family members to get tested. 58 participants were randomly assigned to either receive a video via text message or a traditional letter in the mail. The goal was to see which …

This study tested if mailing HPV self-test kits to women could help more of them get screened for cervical cancer. Researchers compared two groups: one received the home test kit in the mail, and the other received a standard reminder letter to get screened at a clinic. The goal …

This study tested whether group Argentine Tango dance classes could help breast cancer survivors manage chemotherapy side effects better than standard home exercises. Fifty-two survivors with neuropathy symptoms were randomly assigned to either take 16 Tango classes or follow a h…

This study tested whether a 12-week virtual support program could help older adults with advanced lung cancer feel better physically and emotionally during their cancer treatment. One hundred participants were randomly assigned to either receive the program—which included guided …

This study tested whether a 12-week online program could help older adults who have finished cancer treatment. The program provided personalized nutrition advice from dietitians and resistance exercise guidance from exercise scientists, all delivered remotely. Researchers wanted …

This study aimed to understand how new nicotine pouches appeal to people who use smokeless tobacco in rural Ohio and Appalachia. Researchers tested two popular brands of nicotine pouches against participants' usual smokeless tobacco to measure appeal and nicotine delivery. The go…

This study aimed to screen endometrial cancer patients for specific genetic changes in their tumors to better understand their disease. By testing over 1,000 patients, researchers looked for inherited cancer risks and genetic markers that could predict how well treatments might w…

This study aimed to understand how young adults perceive and use e-cigarettes containing a new chemical called 6-methyl nicotine compared to regular nicotine. Researchers enrolled 53 young adult e-cigarette users who tried different vaping products in lab sessions and answered qu…

This study aimed to understand how a person's genetic makeup affects how quickly their body processes a high-dose chemotherapy drug called methotrexate, which is used to treat certain lymphomas. Researchers studied 20 adult patients to see if specific gene variations were linked …

This study aimed to understand how new synthetic cooling agents in cigarettes affect smoking. With menthol cigarettes facing a ban, tobacco companies are adding these flavorless chemicals to mimic menthol's cooling sensation. Researchers tested these new cigarettes on 34 young ad…

This study surveyed 109 breast and prostate cancer patients to understand how often they used vitamins, supplements, and other alternative therapies while undergoing radiation treatment. Researchers asked patients at three different times to see if their use of these therapies ch…

This study tested an online training program for community healthcare providers to improve their knowledge of cancer survivorship care. Twenty-eight nurses, doctors, and other providers from Ohio attended six virtual sessions over 12 weeks. The goal was to see if the training inc…