Experimental combo aims to boost stem cell transplant success for rare blood cancers

NCT ID NCT02512497

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 37 times

Summary

This early-phase study tested whether adding the drug romidepsin to standard chemotherapy before and after a stem cell transplant could help control T-cell cancers like lymphoma and leukemia. Researchers enrolled 23 adults to find the safest dose and see if the combination helped patients engraft and survive at least 30 days. The goal was to improve transplant outcomes, not to cure the disease, and patients would still need long-term monitoring and possibly ongoing treatment.

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Contacts and locations

Locations

  • The Ohio State University Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.