Gene study reveals why some lymphoma patients clear chemo slower

NCT ID NCT06031194

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study examined how genetic variations influence the body's ability to clear high-dose methotrexate in 20 adults with diffuse large B-cell lymphoma or central nervous system lymphoma. Researchers looked for specific gene changes linked to slower drug removal. The goal was to better understand drug metabolism, not to provide a new treatment.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma primary central nervous system lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States