Gene study may predict chemo side effects in lymphoma

NCT ID NCT06031194

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 29 times

Summary

This study looked at how genetic differences affect the body's ability to clear high-dose methotrexate in patients with diffuse large B-cell lymphoma. Researchers analyzed DNA from 20 participants to find gene variations linked to slower drug clearance. The goal was to better understand and predict treatment-related side effects.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

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