CENTRAL NERVOUS SYSTEM LYMPHOMA
Clinical trials for CENTRAL NERVOUS SYSTEM LYMPHOMA explained in plain language.
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New drug combo after radiation shows promise for brain cancer
Disease control Recruiting nowThis early-phase study tests whether two drugs, loncastuximab tesirine and rituximab, given after precise radiation (SRS) are safe and work for people with central nervous system lymphoma. The trial includes 12 adults whose cancer has returned or who cannot take standard chemothe…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE1 • Sponsor: University of Utah • Aim: Disease control
Last updated May 17, 2026 00:46 UTC
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New hope for hard-to-treat brain lymphoma: drug combo trial launches
Disease control Recruiting nowThis study tests a new combination of three drugs (selinexor, methotrexate, and rituximab) for people whose central nervous system lymphoma has come back or not responded to prior treatment. About 30 adults aged 18-75 will take part. The goal is to find the safest dose and see ho…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Tong Chen, MD • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Double-targeting CAR-T cells take on hard-to-treat blood cancers
Disease control Recruiting nowThis study tests a new type of CAR-T cell therapy that targets two proteins (CD19 and CD20) on cancer cells. It is for adults with certain B cell blood cancers (like lymphoma or leukemia) that have not responded to other treatments. The goal is to see if these specially engineere…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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New hope for brain cancer patients: drug cocktail trial opens
Disease control Recruiting nowThis study tests a combination of three drugs (thiotepa, pirtobrutinib, and sintilimab) in 24 people with a type of brain lymphoma that has returned or is hard to treat. The goal is to see if the combo can shrink tumors and improve survival. Participants who respond may get a ste…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE2 • Sponsor: Zhejiang Cancer Hospital • Aim: Disease control
Last updated May 11, 2026 20:41 UTC
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New drug cocktail takes on recurrent brain cancer
Disease control Recruiting nowThis early-phase trial is testing whether combining two drugs, epcoritamab and ibrutinib, is safe for people with central nervous system (CNS) lymphoma that has come back or not responded to treatment. About 26 adults with this rare brain cancer will take part. The main goal is t…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 06, 2026 16:15 UTC
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CAR-T patients monitored for decades in new safety study
Knowledge-focused Recruiting nowThis study follows up to 500 people who received CAR-T cell therapy for blood cancers like leukemia, lymphoma, or multiple myeloma. Researchers will track participants for up to 15 years to see if any new cancers develop. The goal is to understand the long-term safety of this tre…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Brain radiation's hidden toll: new study tracks memory loss in blood cancer patients
Knowledge-focused Recruiting nowThis study follows 100 adults with blood cancers who receive whole brain radiation therapy to see how it affects their memory and thinking skills. Researchers will test cognitive function over time using standard assessments. The goal is to better understand the side effects of t…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 13, 2026 16:04 UTC