CENTRAL NERVOUS SYSTEM LYMPHOMA
Clinical trials for CENTRAL NERVOUS SYSTEM LYMPHOMA explained in plain language.
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New drug combo after brain radiation shows promise for lymphoma patients
Disease control Recruiting nowThis early-phase trial tests whether a combination of two drugs (loncastuximab tesirine and rituximab) given after precise radiation to the brain is safe and effective for central nervous system lymphoma. The study enrolls 12 adults whose lymphoma has returned or who cannot recei…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE1 • Sponsor: University of Utah • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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New drug cocktail targets Hard-to-Treat brain lymphoma
Disease control Recruiting nowThis early-phase study tests whether combining two drugs, epcoritamab and ibrutinib, is safe for people whose central nervous system lymphoma has come back or not responded to treatment. About 26 adults with this rare cancer will receive the drug combination. The main goal is to …
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Brain cancer breakthrough? CAR t cells injected directly into fluid around brain in new trial
Disease control Recruiting nowThis early-phase trial tests a new approach to treat central nervous system (CNS) lymphoma by injecting specially engineered immune cells (CAR T cells) directly into the fluid surrounding the brain. The study involves 20 participants and aims to find the safest dose while monitor…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Double-Barreled attack: CAR-T plus stem cell transplant takes on aggressive lymphoma
Disease control Recruiting nowThis study tests a powerful two-step approach for people with a fast-growing type of lymphoma that has not responded to standard treatments. First, patients receive a CAR-T cell therapy (engineered immune cells) followed by a stem cell transplant with high-dose chemotherapy. The …
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE2 • Sponsor: Zhejiang Cancer Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Double-Target CAR-T therapy takes on tough blood cancers
Disease control Recruiting nowThis phase 1/2 trial is testing a new type of CAR-T cell therapy that targets two proteins (CD19 and CD20) on cancer cells, aiming to improve treatment for people with relapsed or refractory B-cell cancers like lymphoma and leukemia. The study will enroll up to 100 adults and eva…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New hope for brain cancer: Triple-Drug attack shows promise
Disease control Recruiting nowThis study tests a combination of three drugs (thiotepa, pirtobrutinib, and sintilimab) for people with a type of brain lymphoma that has come back or is hard to treat. The goal is to see if this mix can shrink tumors and help patients live longer. About 24 adults will take part,…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE2 • Sponsor: Zhejiang Cancer Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New hope for tough brain cancer: Triple-Drug attack shows promise
Disease control Recruiting nowThis study tests a three-drug combination (selinexor, methotrexate, and rituximab) in 30 adults with central nervous system lymphoma that has relapsed or not responded to treatment. The goal is to find the safest dose and see how well the combo works. Participants receive the dru…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Tong Chen, MD • Aim: Disease control
Last updated Jun 26, 2026 18:24 UTC
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Brain Radiation's hidden toll: new study tracks memory loss in blood cancer survivors
Knowledge-focused Recruiting nowThis study follows 100 adults with blood cancers (like lymphoma or leukemia) who receive whole brain radiation. Researchers will test memory, thinking, and quality of life over time using MRI scans and questionnaires. The goal is to understand how radiation affects the brain, not…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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CAR-T cell patients monitored for 15 years in new study
Knowledge-focused Recruiting nowThis study follows 500 people who received CAR-T cells in earlier trials for blood cancers like lymphoma and multiple myeloma. Researchers will check for new cancers and track long-term safety and effectiveness over 15 years. No new treatment is given; it is purely an observation…
Matched conditions: CENTRAL NERVOUS SYSTEM LYMPHOMA
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC