Ohio State University Comprehensive Cancer Center

This study tests a procedure that uses a thin tube with a camera and ultrasound to guide a needle into pancreatic cysts. Chemotherapy drugs are then injected directly into the cyst to shrink or destroy it. The goal is to prevent these precancerous cysts from developing into pancr…

This study tests whether some people with early-stage breast cancer can safely avoid surgery after chemotherapy and radiation. Participants will be monitored with MRIs, mammograms, and blood tests to check if the cancer stays away. The goal is to see if a non-surgical approach wo…

This study compares two prehabilitation programs—one in-person and one virtual—that combine physical therapy and relaxation techniques for adults with lung cancer who are about to have surgery. The goal is to see if these programs help patients feel stronger, recover faster, and …

This study tests a new tool called the Buckeye Quit Stick to help smokers with lung cancer quit. The stick replaces the hand-to-mouth habit of smoking without using medicine. About 30 people will try it to see if it helps them stay smoke-free.

This study tests a program called FOCUS, delivered through a smartphone app and telemedicine, to help people with advanced cancer manage common symptoms like trouble sleeping, worry, sadness, and fatigue. The goal is to improve quality of life and make these skills accessible to …

This study looks at whether raising taxes on e-cigarettes with features that appeal to young people (like flavors) can discourage teens and young adults from using them, while encouraging adult smokers to switch away from regular cigarettes. About 3,400 participants will respond …

This study looks at whether menthol cigarettes are more addictive than non-menthol ones. About 48 daily smokers who use menthol cigarettes will take part. Researchers will measure nicotine levels, smoking behavior, and how much people like each type in both lab and everyday setti…

This study looks at how adults who regularly use nicotine pouches actually use them. Researchers will measure nicotine levels in the blood and track how people switch between different pouch products. The goal is to gather information that could help shape future rules about thes…

This study looks at whether a spinal tap (lumbar puncture) can find bits of tumor DNA in the fluid around the brain and spine. It includes 40 people with stage III or IV non-small cell lung cancer, who are at risk for brain metastases. The goal is to see if this test can help pre…

This study looks at nicotine analogs, which are chemicals similar to nicotine found in some e-cigarettes. Researchers want to see if these analogs cause cravings and addiction like nicotine does. About 70 adult e-cigarette users will take part in lab visits to share their experie…