New drug combo offers Surgery-Free option for elderly breast cancer patients

NCT ID NCT02760030

First seen Jan 11, 2026 · Last updated May 13, 2026 · Updated 14 times

Summary

This study tested a combination of two hormone-blocking drugs (fulvestrant and palbociclib) in 14 elderly patients with hormone-sensitive breast cancer who either could not undergo surgery due to frailty or chose not to have it. The goal was to see if this drug pair could control the cancer for at least one year without needing surgery. Results showed the treatment was generally manageable, offering a non-surgical option for this older population.

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Contacts and locations

Locations

  • Case Western University

    Cleveland, Ohio, 44106, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • St. Elizabeth Healthcare

    Edgewood, Kentucky, 41017, United States

Conditions

Explore the condition pages connected to this study.