One-Time radiation boost during breast surgery shows promise in Early-Stage cancer trial

NCT ID NCT02927912

First seen Feb 19, 2026 · Last updated Jun 12, 2026 · Updated 19 times

Summary

This study tests whether giving a single dose of radiation directly to the tumor site during breast-conserving surgery (lumpectomy) and before reconstruction is safe and effective for women with early-stage breast cancer. About 108 participants with stage I-II breast cancer will receive this targeted radiation boost. The goal is to kill remaining tumor cells while potentially improving cosmetic results and reducing the need for additional treatments.

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Contacts and locations

Locations

  • Avera Cancer Institute

    Sioux Falls, South Dakota, 57105, United States

  • Centre Hospitalier de I'Universite de Montreal

    Québec, Montreal, H2X0C1, Canada

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • University Hospitals

    Cleveland, Ohio, 44106, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27599, United States

Conditions

Explore the condition pages connected to this study.