Soy pretzels vs. wheat pretzels: a surprising weapon against inflammation?

NCT ID NCT07650409

Ongoing Symptom relief Sponsor: Ohio State University Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares the effects of soy soft pretzels and wheat pretzels on inflammation in 30 men with obesity. Researchers want to see if the natural chemicals in soy can reduce chronic inflammation, which is linked to health problems like cancer. Participants will eat either soy or wheat pretzels and provide blood and urine samples to measure changes in inflammatory markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: soy soft pretzels
What this could lead to: If it works, this could point toward a simple dietary change to help lower chronic inflammation in people with obesity.
What could go wrong: This is a very small, early-stage trial with only 30 participants. The effect may be small or not meaningful, and results may not apply to women or older adults.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer colorectal carcinoma colorectal neoplasm obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CARCINOMA OBESITY-RELATED MALIGNANT NEOPLASM

Contacts and locations

Locations

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States

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