Can reminders and education prevent cervical cancer? a new trial aims to find out.

NCT ID NCT04452526

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether a program that combines educational materials with electronic health record reminders can increase HPV vaccination rates among children and young adults aged 11–26 in four Appalachian states. The goal is to improve vaccine uptake and ultimately prevent cervical cancer. Researchers are comparing clinics that start the program early versus those that start later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

educational materials and reminder letters

What this could lead to

If successful, this approach could help prevent cervical cancer by increasing HPV vaccination rates in underserved communities.

What could go wrong

The trial is relatively small and focuses on a specific region, so results may not apply elsewhere. It tests a behavioral intervention, not a new vaccine or drug.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical carcinoma human papillomavirus-related squamous cell carcinoma Uterine Cervical Neoplasms cervical cancer prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • University of Kentucky/Markey Cancer Center

    Lexington, Kentucky, 40536, United States

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

  • West Virginia University

    Morgantown, West Virginia, 26506, United States