Can reminders and education prevent cervical cancer? a new trial aims to find out.

NCT ID NCT04452526

Ongoing Prevention Sponsor: Ohio State University Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether a program that combines educational materials with electronic health record reminders can increase HPV vaccination rates among children and young adults aged 11–26 in four Appalachian states. The goal is to improve vaccine uptake and ultimately prevent cervical cancer. Researchers are comparing clinics that start the program early versus those that start later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: educational materials and reminder letters
What this could lead to: If successful, this approach could help prevent cervical cancer by increasing HPV vaccination rates in underserved communities.
What could go wrong: The trial is relatively small and focuses on a specific region, so results may not apply elsewhere. It tests a behavioral intervention, not a new vaccine or drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cervical carcinoma human papillomavirus-related squamous cell carcinoma Uterine Cervical Neoplasms cervical cancer prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL CARCINOMA HUMAN PAPILLOMAVIRUS-RELATED MALIGNANT NEOPLASM

Contacts and locations

Locations

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
University of Kentucky/Markey Cancer Center

Lexington, Kentucky, 40536, United States
University of Virginia

Charlottesville, Virginia, 22908, United States
West Virginia University

Morgantown, West Virginia, 26506, United States

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