Nantes University Hospital

This study tested a new drug called FR104 in 10 people receiving a kidney transplant for the first time. The goal was to see if FR104 is safe and can help prevent the body from rejecting the new kidney. Researchers monitored side effects and kidney function over time.

This study tested three emergency treatments for dangerously high potassium levels (hyperkalemia) in 419 adults at emergency departments. It compared insulin/dextrose infusion, nebulized salbutamol, and a combination of both to see which lowers potassium most effectively within 6…

This study looked at whether giving the multiple sclerosis drug natalizumab (Tysabri) at home is as safe as giving it in a hospital. Researchers followed 295 adults with relapsing-remitting MS who had been on the drug for over two years. They compared serious side effects and qua…

This study tested a newer endoscopy method (virtual chromoendoscopy) against the standard Seattle protocol for finding precancerous or cancerous changes in people with Barrett's esophagus. About 110 adults with Barrett's esophagus took part. The goal was to see if the newer metho…

This study looked at 400 adults having scheduled, complex heart surgery to find a better way to detect acute kidney injury early. Researchers combined standard tests with newer biomarkers to create a score that could identify kidney problems within 6 hours after surgery. The goal…

This study tested a set of dermo-cosmetic products (hand/foot serum, nail strengthener, dissolving oil, and gloves/slippers) in 20 multiple myeloma patients receiving a type of immunotherapy called bispecific antibodies. The goal was to see if these natural-based products could p…

This study looked at two ways of wrapping compression bandages for people with open leg ulcers caused by vein problems. One method covered the heel, the other left it uncovered. The goal was to see if leaving the heel out changes the pressure of the bandage or affects comfort. Ab…

This study tested a new treatment for people with long-lasting heel pain (plantar fasciitis) that didn't get better with standard care like physical therapy or steroid shots. The treatment uses a thin needle to gently break up scar tissue and then injects a concentrated solution …

This study aimed to find new blood markers that could show liver damage in people with anorexia nervosa. Researchers compared blood tests from 19 patients with and without signs of liver injury. The goal was to better understand and detect liver problems linked to this eating dis…

This study looked at how gambling disorder affects thinking skills like decision-making and impulse control. Researchers compared 50 people with gambling disorder to healthy volunteers using brain tests. The goal was to find specific mental weaknesses that could be improved with …

This study aims to confirm that measuring two substances in the blood (FLT3L and IL-6) during the first round of chemotherapy can help predict how well patients with acute myeloid leukemia (AML) will do. Researchers will track 201 newly diagnosed AML patients across 25 centers in…

This study looked at 725 severely obese adults (BMI 35 or higher) to find the safest way to place a breathing tube during surgery. Researchers compared two methods: one where patients received face mask ventilation during the procedure and one where they did not. The goal was to …

This study looked at 57 kidney transplant recipients to see if high blood pressure in the first few months after transplant is related to having too much fluid in the body. Participants measured their blood pressure and body fluid levels at home using special devices. The goal wa…

This study looked at 11 women with lung transplants who had babies between 2012 and 2021. Researchers checked if shared immune markers (HLA) between the child and the lung donor increased the risk of organ rejection after pregnancy. The goal is to better understand these risks an…

This study looked at whether two blood tests, eLIFT and FibroMeter, can accurately detect advanced liver fibrosis (scarring) in people with type 2 diabetes. The researchers compared these blood tests to a specialized ultrasound (FibroScan) and, in some cases, liver biopsy. The go…

This study looked at how the calf muscle and Achilles tendon stretch and move during walking in 64 people who had a stroke or spinal cord injury, compared to healthy individuals. Researchers used ultrasound and 3D motion capture to measure these changes. The goal was to better un…

This study looked at how people with Alzheimer's disease or a type of frontotemporal dementia recall personal memories. Researchers analyzed whether memories were specific events or more general. The goal was to better understand memory loss patterns, not to test a treatment. 39 …

This study used health records from 2 million adults in France to see if people who had pneumonia are more likely to develop heart problems later. Researchers compared those who had pneumonia with similar people who did not, tracking heart attacks, strokes, and other major heart …

This study looked at the bacteria living in the lungs of 82 healthy volunteers scheduled for non-lung surgery. Researchers used advanced techniques to analyze both the bacteria and the immune cells in the lungs. The goal was to create a detailed atlas of how the lungs' natural ba…

This study looked at 88 young children (3 months or younger) who had heart surgery with a heart-lung machine. Researchers measured certain immune markers in the blood to see if the surgery causes an immune system shutdown. The goal was to understand how the body responds, not to …

This study tested whether a special oral hygiene program helps children with cleft deformities keep their teeth and gums healthier. Sixty children aged 3 to 15 took part. Researchers measured tooth decay and gum health to see if the program made a difference.

This study looked at whether wearing a sleeve under a blood pressure cuff changes the reading. Researchers tested 75 intensive care patients who already had an arterial line (the most accurate method). They compared readings taken on bare skin, over a thin sleeve, and over a thic…

This study looked at eye problems in 100 adults with atopic dermatitis (eczema) who were treated with tralokinumab. The main goal was to find out how often eye issues like conjunctivitis happen with this medication. Researchers followed participants for 4 months to track any new …

This study looked at how common liver scarring (fibrosis) is in people with anorexia nervosa. Researchers used a special scan called Fibroscan to measure liver stiffness in 43 patients admitted to the hospital. The goal was simply to find out how many had liver damage, not to tes…

This study looked at 346 adults who had a cardiac arrest outside the hospital. Doctors used an ultrasound within the first 12 minutes of CPR to see if the heart was still. The goal was to find out if a still heart on ultrasound can predict that the heart won't start beating again…

This study looked at how the COVID-19 pandemic affected online gambling in France and Sweden. Researchers analyzed data from 120,000 gamblers to see if lockdowns and stress led to more gambling. The goal was to understand changes in gambling habits and identify groups at risk for…