Spirulina supplement tested to stop chemo nerve pain

NCT ID NCT05025826

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether Phycocare, a supplement made from spirulina, can reduce nerve damage caused by the chemotherapy drug oxaliplatin in people with metastatic gastrointestinal cancers. 73 participants took either Phycocare or a placebo daily for 9 months. The goal was to see if Phycocare could cut the rate of moderate-to-severe neuropathy by half at 4 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Phycocare (phycocyanin from spirulina)

What this could lead to

If it works, this could offer a way to prevent or reduce painful nerve damage caused by oxaliplatin chemotherapy, helping patients stay on treatment longer.

What could go wrong

This is a small, early-stage trial with only 73 participants. The supplement may not reduce neuropathy more than placebo, and results may not apply to all cancer types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

digestive system cancer gastric cancer gastric neoplasm toxic encephalopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier de Cholet

    Cholet, 49300, France

  • Chd La Roche Sur Yon

    La Roche-sur-Yon, France

  • Clermont-Ferrand UH

    Clermont-Ferrand, France

  • Foch Suresnes Hosptial

    Suresnes, France

  • Hôpital le Confluent

    Nantes, 44000, France

  • Mutaliste Clinic Saint Nazaire

    Saint-Nazaire, France

  • Nantes Uh

    Nantes, France

  • Saint Gregoire Clinique

    Rennes, France