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Blood test may spare thousands of kids from unnecessary CT scans after head injury

NCT ID NCT05413499

Completed Diagnosis Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether measuring two proteins in the blood (GFAP and UCH-L1) can help doctors safely avoid CT scans in children with mild traumatic brain injury. Over 1,500 children across Europe participated. The goal was to see if these blood tests are accurate enough to detect serious brain injuries and predict recovery, potentially reducing radiation exposure from CT scans.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRAUMATIC BRAIN INJURY

Contacts and locations

Locations

  • Armand Trousseau hospital (AP-HP)

    Paris, France

  • Brest University Hospital

    Brest, France

  • Clermont-Ferrand University Hospital

    Clermont-Ferrand, France

  • Grenoble University Hospital

    Grenoble, France

  • Hospital 12 de Octubre

    Madrid, Spain

  • Hospital Infantil Universitario Nino Jesus

    Madrid, Spain

  • Hospital Universitari Vall d'Hebron (ICS)

    Barcelona, Spain

  • Klinikum rechts der Isar, Technical University of Munich

    Munich, Germany

  • La Roche/Yon Hospital

    La Roche-sur-Yon, France

  • Lille University Hospital

    Lille, France

  • Limoges University Hospital

    Limoges, France

  • Lorient Hospital

    Lorient, France

  • Louis Mourier Hospital (AP-HP)

    Colombes, France

  • Luzerner Kantonsspital

    Lucerne, Switzerland

  • Montpellier University Hospital

    Montpellier, France

  • Nantes University Hospital

    Nantes, France

  • Rennes University Hospital

    Rennes, France

  • Robert Debré Hospital (AP-HP)

    Paris, France

  • Saint Etienne University Hospital

    Saint-Etienne, France

  • Saint Nazaire Hospital

    Saint-Nazaire, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.